Dr. Mohammad Reza Abbaspour PhD of pharmaceutics Assistant professor Department of Pharmaceutics, School of Pharmacy & Nanotechnology Research Centre Ahvaz Jundishapur University of Medical Sciences P.O. Box: 61357-33184, Ahvaz, Iran Tel / fax: +98 611 3738381 E-mail:[email protected]; [email protected] Education: - Ph.D of pharmaceutics, School of Pharmacy, Mashhad University of Medical Science )2000-2006( - A 6 months scholarship in SLN formulation, School of pharmacy, University of Toronto, Canada (2005) - Pharm. D from School of Pharmacy, Mashhad University of Medical Science )1993 -1999( Research interests: Modified and Sustained Release formulations; Multiparticulates; Pelletization; Tabletting; Coating; Solid Lipid Nanoparticles (SLN); Nanofiber; Application of Experimental Design in formulation optimization Experiences: Operating screw extruder, spheronizer, fluidized bed coating, tabletting machine, electrospinning, dissolution test, material testing machine, DSC and… Statistical and graphical softwares such as SPSS, Sigma plot, Instat, Image analysis, Microsoft Excel and … Publications: 1- Sajadi Tabassi, S.A., Rajabi, O., Shafiee Nik, R., Abbaspour, M.R., 2002, A new solid dosage form of Insulin: Release and stability studies, Iranian Journal of Basic Medical Sciences, 5(2), 9-14. (Persian) 2- Abbaspour, M. R., Sadeghi, F., Afrasiabi Garekani, H., 2005. Preparation and characterization of ibuprofen pellets based on Eudragit RS PO and RL PO or their combination. Int. J. Pharm., 303, 88- 94. 3-Abbaspour, M.R., Sadeghi, F., Afrasiabi Garekani, H., 2005. Effect of drug loading on physicomechanical and release properties of ibuprofen pellets prepared by Extrusion-Spheronization, Journal of Pharm. Sci., 2 , 55-64. (Persian) 4-Abbaspour, M.R., Sadeghi, F., Afrasiabi Garekani, H., 2007. Thermal treating as a tool to produce plastic pellets based on Eudragit RS PO and RL PO aimed for tableting. Eur. J. Pharm. Biopharm., 67, 260-267. 5-Abbaspour, M.R., Sadeghi, F., Afrasiabi Garekani, H., 2008. Design and Study of Ibuprofen Disintegrating Sustained-Release Tablets Comprising Coated Pellets. Eur. J. Pharm. Biopharm.,68, 747-759.
6-Abbaspour, M.R., Alimorad, M., Beygi, I., 2009. Preparation and evaluation of diclofenac sodium multiparticulate tablets by extrusion-spheronization. Journal of Pharm. Sci., 15(2), 183- 194. (Persian) 7- Abbaspour, Z., Goudarzi, F., Abbaspour, M.R., 2010. Comparison effects of vitamin C vaginal tablet and metronidazole vaginal gel on treatment and relapse of bacterial vaginosis. Sci. Med. J., 8(4), 423-430. (Persian) 8- Sharif Makhmalzadeh, B., Jamei, T., Rahim, F., Abbaspour, M.R., 2010. Multiple unite sustained released floating of sodium diclofenac: Formulation and evaluation using factorial design. Int. J. Drug Deliv., 2(4), 344-351. 9- Abbaspour, M.R., Sharif Makhmalzadeh, B., Jalali, S. 2010. Study of free-films and coated tablets based on HPMC and microcrystalline cellulose, aimed for improve stability of moisture- sensitive drugs, Jundishapur J. Natural Pharm. Prod.,5(1), 9-18.
10- Abbaspoor, Z., Goodarzy, F., Abbaspour, M.R., Comparison of the effectiveness of vitamin C vaginal tablet with metronidazole vaginal gel in the treatment of bacterial vaginosis, Afr. J. Pharm. Pharmacol., 2010; 4(7), 484-489. 11- Shahbazian, H., Zafar Mohtashami, A., Ghorbani, A., Abbaspour, M.R., Belladi Musavi, S.S., Hayati, F., Lashkarara, G.R. Oral nicotinamide reduces serum phosphorus, increases HDL, and induces thrombocytopenia in hemodialysis patients: a double-blind randomized clinical trial, Nefrologia, 2011; 31(1): 58-65. 12- Makvandi, S., Tadayon, M., Abbaspour, M.R. Effect of hyoscine-N-butyl bromide rectal suppository on improvement of labour in primigravid women: A randomized, double-blind placebo- controlled clinical trial, Croat. Med. J., 2011; 52(2):159-163. 13- Akhgari, A., Abbaspour, M.R., Rezaee, S., Kuchak, A. Evaluation of swelling. Erosion and drug release from polysaccharide matrix tablets based on pectin and inulin, Jundishapur J. Natural Pharm. Prod., 2011; 6 (1): 51-58.
Presentations: 1- Abbaspour, M.R., Rajabi, O., Sajadi Tabassi, S.A., Shafiee Nik, R., 2002, An investigation to the formulation of a new solid dosage form of Insulin, The first national pharmacy students seminar in industry and therapeutic, Ahwaz, Iran, Nov 2001. (Lecture) 2- Abbaspour, M.R., Afrasiabi-Garekani, H., Sadeghi, F., Effect of drug loading on physicomechanical and release properties of ibuprofen pellets prepared by Extrusion-Spheronization. 9th Iranian Pharmaceutical Science Conference. Tabriz, Iran, Aug 2004. 3- Afrasiabi-Garekani, H., Sadeghi, F., Abbaspour, M.R., Development of Eudragit based pellets of ibuprofen and effect of curing on their characteristics. 12th international pharmaceutical technology symposium. Istanbul, Turkey, Sep 2004. 4- Sadeghi, F., Abbaspour, M.R., Afrasiabi Grekani, H., Preparation and characterization of ibuprofen pellets based on Eudragit RS and RL or their combination. Biritish Pharmaceutical Conference, Manchester, UK, Sep. 2004, Published: J. Pharm. Pharmacol., 56 (suppl.), S-18
5- Sadeghi, F., Abbaspour, M.R., Afrasiabi Grekani, H., Effect of thermal treating on release and physicomechanical properties of ibuprofen pellets based on Eudragit RS and RL. 2nd EUFEPS Conference, Versailles, France, Nov 2005. 6- Li, Y., Abbaspour, M.R., Rauth, A.M., Wu, X.Y., Artificial Neural Networks plus Evolutionary Algorithms Based Modeling and Optimization in the Rational Design of Pharmaceutical Formulations, AAPS annual meeting and exposition, Nashville, USA, Nov 2005. 7- Abbaspour, M.R., Sadeghi, F., Afrasiabi-Garekani, H., Tabletting of Eudragit based ibuprofen pellets coated with Eudragit RS and RL. 10th Iranian Pharmaceutical Science Conference. Tehran, Iran, Aug 2006. 8- Li, Y., Abbaspour, M.R., Rauth, A.M., Wu, X.Y., Rational design of polymer-lipid hybrid nanoparticles (PLN), 33rd Annual meeting and exposition of controlled release society, Vienna, Austria, Jul 2006. 9- Sadeghi, F., Abbaspour, M.R., Tayarani, F., Afrasiabi Grekani, H., Mechanical and release behavior of ibuprofen pellets based on Eudragit RL plasticized with triethylcitrate. Biritish Pharmaceutical Conference, Manchester, UK, Sep. 2006, Published: J. Pharm. Pharmacol., suppl. 1, A-78. 10- Li, Y., Abbaspour, M.R., Rauth, A.M., Wu, X.Y., Rational design of polymer-lipid hybrid nanoparticles (PLN) for the delivery of ionic drugs, AAPS annual meeting and exposition, San Antonio, USA, Oct 2006.
11- Abbaspour, M.R., Sadeghi, F., Afrasiabi-Garekani, H., Design and study of ibuprofen multiparticulate sustained-release tablets. 3rd Iranian Conference of Novel Drug Delivery Systems. Tehran, Iran, Jun 2007. (Lecture) 12- Sadeghi, F., Abbaspour, M.R., Afrasiabi Grekani, H., The effect of coating level on mechanical and release properties of cured eudragit based ibuprofen pellets. 3rd Pharmaceutical Sciences World Congress, Amsterdam, Netherlands, Apr 2007. 13- Abbaspour, M.R., Li, Y., Rauth, A.M., Wu, X.Y., Polymer-lipid hybrid nanoparticles (PLN) for the delivery of ionic drugs, 2nd International Congress on Nanoscience & Nanotechnology, Tabriz, Iran, Oct 2008. (Lecture)
13- Abbaspourm, M. R., Electrospinning: applications in drug delivery, Seminar on applications of nanotechnology in medical sciences, Ahvaz, Iran, Mar 2009. (Lecture)
14- Kuchak, M., Avadi, M.R., Abbaspour, M.R., Jahangiri, A., Kargar Boldaji, S., Determination of insulin in pharmaceuticals by RP-HPLC with UV detection: evaluationof the effect of detection wavelength on accuracy and precision of method, 9th International Symposium on Pharmaceutical Sciences, Ankara, Turkey, Jun 2009.
15- Kouchak, M., Avadi, M.R., Abbaspour, M.R., Jahangiri, A.R., Kargar Boldaji, S., Preparation of nanoparticles containing insulin using high molecular weight chitosan , The Specialized Congress and Exhibition of Nanomedicine, Nanobiotechnology, Nanobiosensors and Nanomaterials, Mashhad, Iran, July 2009
16- Abbaspour, M.R., Alimorad, M., Beygi, I., Effect of curing and tableting on thermomechanical and release properties of Eudragit-based diclofenac sodium pellets, 3rd BBBBinternational Conference on Pharmaceutical Sciences, Antalya, Turkey, Oct 2009. Published: Eur. J. Pharm. Sci., 38(1), suppl., 66-67. 17- Abbaspour, M.R., Makhmalzadeh, B., Jalali, S., Study of free-films and coated tablets based on HPMC and Microcrystalline cellulose, and their comparison with Sepifilm, 12th Iranian Pharmaceutical Sciences Congress, Zanjan, Iran, Aug 2010. 18- Abbaspour, M.R., Akhgari, A., Beygi, V., Comparison effect of some NSAIDs on permeability and thermomechanical behavior of Eudragit RS free films, 12th Iranian Pharmaceutical Sciences Congress, Zanjan, Iran, Aug 2010. 19- Kouchak, M., Avadi, M., Abbaspour, M.R., Jahangiri, A., Kargar Boldaji, S., Effect of insulin chitosan ratio on drug loading efficiency of prepared nanoparticles using ion gelation method, 12th Iranian Pharmaceutical Sciences Congress, Zanjan, Iran, Aug 2010. 20- Kouchak, M., Avadi, M., Abbaspour, M.R., Jahangiri, A., Kargar Boldaji, S., Preparation of nanoparticles containing insulin using three different molecular weights of chitosan and optimization of method to obtain maximum drug encapsulation efficiency, 12th Iranian Pharmaceutical Sciences Congress, Zanjan, Iran, Aug 2010. 21- Abbaspour, M.R., Akhgari A., Beygi V., Effect of indomethacin on thermomechanical properties and permeability of Eudragit RS and Eudragit S100 free films, 70th FIP World Congress of Pharmacy and Pharmaceutical Sciences, Lisbon, Portugal, Aug 2010. 22- Abbaspour, M.R., Polymeric Nanofibers: a new idea in novel drug delivery systems, 1st national congress of nanodrugs, Ahvaz, Iran, Feb 2011. (Key Lecture)
Thesis Supervision (or consultation):
1- Formulation of sodium diclofenac sustained-release pellets by extrusion-spheronization for preparation of multiparticulate tablets. (S) Pharm. D thesis, 2007-2008.
2- Preparation of nanoparticles containing insulin and optimization of method to obtain maximum drug loading efficiency. (C) Pharm. D thesis, 2007-2009
3- Comparison effect of vitamin C vaginal tablet with metronidazole vaginal gel on treatment and relapse of bacterial vaginosis. (S) M.Sc thesis, 2007-2008
4- Study and evaluation of plastisizing effect of some NSAIDs on physical, thermomechanical and permeability characteristics of free films based on acrylic copolymers. (S) Pharm. D thesis, 2008-2010
5- Comparison efficacies of ethanol extract of licorice and clotrimazole vaginal cream on treatment of vaginal candidiasis. (C) M.Sc thesis, 2008-2009
6- Study of free-films and coated tablets properties based on HPMC and microcrystalline cellulose, and their comparison with Sepifilm® aimed for improve stability of moisture-sensitive drugs. (S) Pharm. D thesis, 2008
7- Evaluation of swelling and drug release from matrices based on pectin and inulin. (S) Pharm. D thesis, 2008
8- Preparation and evaluation of 5-aminosalycilic acid pellets by extrusion-spheronization aimed for colon delivery. (S) Pharm. D thesis, 2008
9- Preparation of diclofenc sustained release floating granules based on lipid carriers. (S) Pharm. D thesis, 2008
10- The effect of hyoscine-NBB suppository on labour pain and process in nulliparous women. (C) M.Sc thesis, 2008-2010
11- Preparation and evaluation of ibuprofen and theophylline pellets by extrusion-spheronization using tragacanth and acacia as binder. (S) Pharm. D thesis, 2010-2011
12- Optimization and evaluation of clindamycin phosphate solid lipid nanoparticles using anionic polymers aimed for ocular drug delivery. (S) Pharm. D thesis, 2010
13- Assessment of the effects of oral Niacinamide in reduction of serum phosphorus in hemodialysis patients attending hemodialysis ward of Imam Khomeini Hospital of Ahvaz in 2010. (C) Fellowship thesis, 2009
14- The effect of hyperium perforatum on early menopausal symptoms. (C) M.Sc thesis, 2009-2010
15- The comparison of hyaluronic acid vaginal suppository with vitamin E in the treatment of atrophic vaginitis in menopausal women. (C) M.Sc thesis, 2010-2011
16- Preparation and evaluation of chitosan-PLA nanofibrous film containing mafenide acetate by electrospinning technique. (S) Pharm. D thesis, 2011
17- Preparation and evaluation of pellets containing a self-emulsifying drug delivery system (SEDDS) of loratadine by extrusion-spheronization. (S) Pharm. D thesis, 2011
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From the Richard J. Fox Center for Biomedical Physics, Temple University School of Medicine,Philadelphia, USA The biological effects of millimetre waves (MWs) attion resides in Soviet/Russian/Ukrainian reports onpower levels <20 mW/cm2 were first discovered inthe late 1960s, and within 10 years were studied inHowever, their analysis allows us to reveal somevarious countries including the
Dr. Mohammad Reza Abbaspour