J-k-larsen.dk

Jørgen K. Larsen - Finsen Laboratory - Publications Møller U, Larsen JK, Faber M: The influence of injected tritiated thymidine on the mitotic circadian rhythm in the epithelium of the hamster cheek pouch. Cell Tissue Kinet 7: 213-239, 1974. Hart Hansen O, Pedersen T, Larsen JK: A method to study cell proliferation kinetics in human gastric mucosa. Gut 16: 23-27, 1975. Krøll J, Larsen JK, Loft H, Ezban M, Wallevik K, Faber M: DNA-binding proteins in Yoshida ascites tumor fluid. Biochim Biophys Acta 434: 490-501, 1976. Hart Hansen O, Pedersen T, Larsen JK: Cell proliferation kinetics in normal human gastric mucosa: Studies on diurnal fluctuations and effects of food ingestion. Gastroenterology 70: 1051-1054, 1976. Hart Hansen O, Pedersen T, Larsen JK, Rehfeld JF: The effect of gastrin on gastric mucosal cell proliferation in man. Gut 17: 536-541, 1976. Hart Hansen O, Johansen A, Larsen JK, Pedersen T, Rehfeld JF: Is gastrin a trophic hormone for human gastric mucosa? Current Views in Gastroenterol 1: 199-206, 1977. Larsen JK: Cellekinetisk analyse ved pulscytofotometri. Ugeskr Læg 139: 1115-1117, 1977. Hart Hansen O, Johansen Aa, Larsen JK, Pedersen T, Svendsen LB: Relationship between gastric acid secretion, histopathology, and cell proliferation kinetics in human gastric mucosa. Gastroenterol 73: 453-456, 1977. Hart Hansen O, Jensen KB, Larsen JK, Søltoft J: Gastric mucosal cell proliferation and immunoglobulin containing cells in Ménétriérs disease. Digestion 16: 293-298, 1977. 10. Larsen JK, Pedersen T: Pulsecytophotometry on bladder-washings. In: Pulse-Cytophotometry III. D. Lutz (ed), pp 11. Møller U, Larsen JK, Frentz G: Experimental studies on stratified squamous keratinizing epithelia by pulse- cytophotometry. In: Pulse-Cytophotometry III. D. Lutz (ed), pp. 343-350. European Press, Ghent, 1978. 12. Christensen I, Hartmann NR, Keiding N, Larsen JK, Noer H, Vindeløv L: Statistical analysis of DNA distributions from cell populations with partial synchrony. In: Pulse-Cytophotometry III. D. Lutz (ed), pp. 71-78. European Press, Ghent, 1978. 13*. Hart Hansen O, Larsen JK, Svendsen LB: Changes in gastric mucosal cell proliferation after antrectomy or vagotomy in man. Scand J Gastroenterol 13: 947-952, 1978. 14. Pedersen T, Larsen JK: Flow-cytometri på blæreskyllevand. Ugeskr Læg 4: 351-355, 1978. 15*. Pedersen T, Larsen JK, Krarup T: Characterization of bladder tumours by flowcytometry on bladder washings. Eur 16*. Møller U, Larsen JK: The circadian variations in the epithelial growth of the hamster cheek pouch. Quantitative analysis of DNA distributions. Cell Tissue Kinet 11: 405-413, 1978. 17*. Larsen JK, Nielsen O: Flowcytometrical evaluation of the DNA distribution in isolated pancreatic islets from normal and diabetic mice. J Histochem Cytochem 27: 410-412, 1979. 18*. Møller U, Larsen JK: DNA flowcytometry on isolated keratinized epithelia. A methodological study based on ultrasonic tissue disaggregation. Cell Tissue Kinet 12: 203-212, 1979. 19. Hart Hansen O, Larsen JK, Svendsen LB: Gastrin, the vagus and gastric mucosal cell proliferation in man. In: Gastrins and the vagus; Rehfeld JF, Amdrup E (eds), pp. 259-262. Academic Press, London, 1979. 20*. Hart Hansen O, Johansen Aa, Larsen JK, Svendsen LB: Cell proliferation in normal and diseased gastric mucosa. Autoradiography after in vitro continuous labeling with tritiated thymidine. Acta Pathol Microbiol Scand, Sect A, 87: 217-222, 1979. 21. Christensen I, Møller U, Larsen JK: The choice of model for deconvolution of DNA distributions measured by flow cytometry. In: Flow Cytometry IV. Lærum OD, Lindmo T, Thorud E (eds), pp. 147-151. Universitetsforlaget, Bergen, 1980; and in: Acta Pathol Microbiol Scand Sect A, Suppl 274: 147-151, 1981. 22. Møller U, Larsen JK, Hendel J, Christensen IJ: The cell kinetic effects of methotrexate on the epithelium of the hamster cheek pouch, a circadian dependent effect. In: Flow Cytometry IV. Lærum OD, Lindmo T, Thorud E (eds), pp. 372-376. Universitetsforlaget, Bergen, 1980; and in: Acta Pathol Microbiol Scand Sect A, Suppl 274: 372-376, 1981. 23. Larsen JK, Byskov AG, Grindsted J: Growth and differentiation of fetal mouse gonads in culture studied by flow cytometry on nuclear suspensions. In: Flow Cytometry IV. Lærum OD, Lindmo T, Thorud E (eds), pp. 178-182. Universitetsforlaget, Bergen, 1980; and in: Acta Pathol Microbiol Scand Sect A, Suppl 274: 178-182, 1981. 24. Hart Hansen O, Pedersen T, Svendsen LB, Larsen JK: Gastric mucosal cell proliferation in duodenal ulcer patients. Scand J Gastroenterol, Suppl 63, 15: 89-92, 1980. 25. Lernmark Å, Nielsen DA, Nielsen O, Larsen JK: Light scattering analysis of rodent islet cells. Uppsala Med J 86: 26. Hendel L, Larsen JK, Ammitzbøll T, Asboe-Hansen G: Epithelial cell turnover in the small intestine of psoriatics. In: Psoriasis; Farber EM, Cox AJ, Nall L, Jacobs PH (eds), pp. 331-332. Grune & Stratton, New York, 1982. 27. Westergaard L, Christensen I, Larsen JK, McNatty KP, Frölich M: Follicular health and atresia determined by flow cytomety on aspirated granulosa cells and by steroid content of the follicular fluid. In: Follicular Maturation and Ovulation; Rolland R, van Hall EV, Hillier SG, McNatty KP, Schoemaker I (eds), pp 188-192. Elsevier/North-Holland, Amsterdam, 1982. 28*. Wallevik K, Jensenius J, Larsen JK, Krøll J, Lassota H: An inhibitor of DNA-synthesis, isolated from rat tumor induced ascites. Virchows Arch B Cell Pathol 39: 145-158, 1982. 29*. Westergaard L, McNatty KP, Christensen I, Larsen JK, Byskov AG: Flow cytometric DNA-analysis of granulosa cells aspirated from human ovarian follicles. A new method to distinguish healthy and atretic ovarian follicles. J Clin Endocrinol Metab 55: 693-698, 1982. 30*. Nielsen O, Larsen JK, Christensen IJ, Lernmark Å: Flow sorting of mouse pancreatic B-cells by forward and orthogonal light scattering. Cytometry 3: 177-181, 1982. 31*. Søndergaard K, Larsen JK, Møller U, Christensen IJ, Hou-Jensen K: DNA ploidy-characteristics of human malignant melanoma analysed by flow cytometry and compared with histology and clinical course. Virchows Arch B Cell Pathol 42: 43-52, 1983. 32*. Lange Wantzin G, Thomsen K, Larsen JK, Christensen IJ, Bruun Rasmussen B: DNA analysis by flow cytometry in lymphomatoid papulosis. Clin Exp Dermatol 8: 505-512, 1983. 33*. Lange Wantzin G, Larsen JK, Christensen IJ, Bruun Rasmussen B: Aneuploidy in cutaneous T-cell lymphoma. Acta Dermatol Venerol 63: 283-289, 1983. 34*. Geisler, Ralfkiær E, Astrup L, Christensen I, Dickmeiss E, Mørk Hansen M, Larsen JK, Petersen J, Plesner T: Chronic lymphocytic leukemia of T cell origin. Clinical variation possibly due to involvement of different T lymphocyte subpopulations. Scand J Haematol 31: 109-121, 1983. 35*. Byskov AG, McNatty KP, Westergaard L, Larsen JK, Grindsted J, Peters H: Abnormal growth of ovarian antral follicles in breast cancer patients. Fertil Steril 40: 73-79, 1983. 36. Geisler C, Mørk Hansen M, Plesner T, Ralfkiær E, Philip P, Larsen JK: Kronisk lymfatisk leukæmi. En oversigt over nyere undersøgelsesmetoder. Ugeskr Læg 146: 265-270, 1984. 37*. Lange Wantzin G; Larsen JK, Christensen IJ, Ralfkiær E, Thomsen K: Early diagnosis of mycosis fungoides by DNA-flow cytometry on skin biopsies. Cancer 54: 1348-1352, 1984. 38*. Krøll J, Larsen JK, Christensen IJ: Tumor-induced growth-inhibitory activity isolated from the Yoshida ascites fluid by extraction with methanol. Eur J Cancer Clin Oncol 20: 783-790, 1984. 39*. Lange Wantzin G, Thomsen K, Brandrup F, Larsen JK: Lymphomatoid papulosis - development into cutaneous T- cell lymphoma. Arch Dermatol 121: 792-794, 1985. 40*. Hendel L, Larsen JK, Ammitzbøll T, Asboe-Hansen G: A study of cell proliferation kinetics in the small intestinal epithelium of psoriatic patients. Clin Exp Dermatol 9: 329-335, 1984. 41*. Møller U, Keiding N, Larsen JK: The effect of methotrexate on cells in a keratinized epithelium with an active thymidine salvage pathway. Cell Tissue Kinet 17: 497-507, 1984. 42*. Møller U, Larsen JK, Keiding N, Christensen IJ: Circadian-stage dependance of methotrexate in a keratinized epithelium. An in-vivo study using flow cytometry on the hamster cheek pouch epithelium. Cell Tissue Kinet 17: 483-495, 1984. 43. Nielsen HI, Christensen IJ, Larsen JK, Madsen AM, Wallevik K: Formation and loss of tumor cell clones during cultivation of human melanomas, assessed by flow cytometrical DNA analysis. In: Pigment Cell 1985. Bognara J, Klaus SN, Paul E, Schartl M (eds), pp. 493-499. University of Tokyo Press, Tokyo, 1985. 44*. Lykkesfeldt AE, Larsen JK, Christensen IJ, Briand P: Effects of the antioestrogen tamoxifen on the cell cycle kinetics of the human breast cancer cell line, MCF-7. Br J Cancer 49: 717-722, 1984. 45*. Nissen MH, Plesner T, Larsen JK, Olesen BK, Ernst P: Enhanced expression in vivo of HLA-ABC antigens and β- 2-microglobulin on human lymphoid cells induced by human interferon-α in patients with lung cancer. Enhanced expression of class I major histocompatibility antigens prior to treatment. Clin Exp Immunol 59: 327-335, 1985. 46*. Lange Wantzin G, Ralfkiær E, Larsen JK, Thomsen K: Clonal evolution in cutaneous malignant histiocytosis. Clin 47*. Lange Wantzin G, Saxinger WC, Woods A, Larsen JK, Thomsen K, Gallo RC: Human T-cell leukemia virus in cutaneous T-cell lymphoma in Denmark. A possible association of HTLV and aneuploidy. Acta Dermato-Venerol 64: 395-399, 1984. 48*. Ralfkiær E, Lange wantzin G, Larsen JK, Christensen IJ, Thomsen K: Single cell DNA measurements in benign cutaneous lymphoid infiltrates and in positive patch tests. Br J Derm 112: 253-262, 1985. 49*. Frentz G, Møller U, Larsen JK: DNA flow cytometry on human epidermal tumours. Intra- and intertumour variability in ploidy and proliferative characteristics. Virchows Arch B Cell Pathol 48: 175-183, 1985. 50*. Larsen JK, Frentz G, Møller U, Christensen IJ: A method for flow cytometric cell cycle analysis of normal and psoriatic human epidermis based on a detergent/citric acid technique for suspension of nuclei. Virchows Arch B Cell Pathol 48: 247-259, 1985. 51. Geisler C, Plesner T, Ralfkiær E, Larsen JK, Hansen MM: Cell markers in lymphoproliferative disease. (Letter in) 52*. Ralfkiær E, Lange Wantzin G, Larsen JK, Andersen V, Geisler C, Thomsen K: Sézary syndrome: phenotypic and functional characterization of the neoplastic cells. Scand J Haematol 34: 385-393, 1985. 53*. Larsen JK, Munch-Petersen B, Christiansen J, Jørgensen K: Flow cytometric discrimination of mitotic cells: Resolution of M, as well as G1, S, and G2 phase nuclei with mithramycin, propidium iodide, and ethidium bromide after fixation with formaldehyde. Cytometry 7: 54-63, 1986. 54*. Lange Wantzin G, Larsen JK, Christensen IJ, Ralfkiær E, Tjalve M, Lund Kofoed M, Thomsen K: Activated and cycling lymphocytes in benign dermal lymphocytic infiltrates including psoriatic skin lesions. Arch Derm Res 278: 92-96, 1985. 55*. Lund Kofoed M, Munch-Petersen B, Larsen JK, Lange Wantzin G: Non-replicative DNA synthesis detected in peripheral lymphocytes from a patient with actinic reticuloid. Photodermatol Clin Exp 3: 158-163, 1986. 56*. Lykkesfeldt AE, Larsen JK, Christensen IJ, Briand P: Cell cycle analysis of estrogen stimulated growth of the human breast cancer cell line, MCF-7. Eur J Cancer Clin Oncol 22: 439-444, 1986. 57*. Larsen JK, Byskov AG, Christensen IJ: Flow cytometry and sorting of meiotic prophase cells of female rabbits. J 58*. Mortensen BT, Hartmann NR, Christensen IJ, Larsen JK, Kristensen T, Wieslander SB, Nissen NI: Synchronization of the human promyelocytic cell line HL 60 by thymidine. Cell Tissue Kinet 19: 351-364, 1986. 59. Lykkesfeldt AE, Larsen JK, Christensen IJ: Cell cycle analysis of estrogen stimulation and anti-estrogen inhibition of growth of the human breast cancer cell line MCF-7. In: Breast Cancer Research and Treatment 7 (Suppl): 83-90, 1986. 60*. Svendsen LB, Hart Hansen O, Larsen JK, Pedersen T, Johansen Aa: Effect of cimetidine on gastric mucosal cell proliferation in man. Scand J Gastroenterol 21: 1271-1274, 1986. 61*. Svendsen LB, Hart Hansen O, Larsen JK, Johansen Aa, Stener Jørgensen F: The effect of acetyl salicylic acid and indometacin on cell proliferation kinetics in the human gastric mucosa. Scand J Rheumatol 16: 107-111, 1987. 62*. Vejerslev LO, Larsen JK, Christensen IJ, Tommerup N: DNA-aneuploidy in 46,XX hydatidiform moles. Cancer 63*. Stenstrand K, Larsen JK, Wulf HC, Lange Wantzin G: Effects of 254 nm UV irradiation of human lymphocytes in vitro studied on chromosomes, cell cycle phase distribution and cell surface antigens. Photodermatol 4: 36-42, 1987. 64*. Geisler CH, Larsen JK, Plesner T, Hansen M, Hansen MM: Lack of prognostic significance of T-lymphocyte subset counts i B-cell chronic lymphocytic leukemia. Eur J Haematol 38: 67-74, 1987. 65*. Svendsen LB, Stener Jørgensen F, Hart Hansen O, Johansen A, Horn T, Larsen JK: Influence of the prostaglandin E1 analogue rioprostil on the human gastric mucosa. Digestion 37: 29-34, 1987. 66*. Nissen MH, Larsen JK, Plesner T, Olesen BK, Ernst P: α-interferon induces enhanced expression of HLA-ABC antigens and β-2-microglobulin in vivo and in vitro in various subsets of human lymphoid cells. Clin Exp Immunol 69: 632-638, 1987. 67. Larsen JK, Christiansen J: Flow cytometric discrimination of mitotic nuclei by forward and orthogonal light scatter. In: Clinical Cytometry and Histometry; Burger G, Ploem JS, Goerttler K (eds), pp. 279-281. Academic Press, London, 1987. 68*. Geisler C, Plesner T, Pallesen G, Skjødt K, Ødum N, Larsen JK: Characterization and expression of the human T cell receptor-T3 complex by monoclonal antibody F101.01. Scand J Immunol 27: 685-696, 1988. 69*. Geisler C, Larsen JK, Plesner T: Identification of alpha beta and gamma delta T cell receptor positive cells. Scand 70*. Lykkesfeldt A, Balslev I, Christensen IJ, Larsen JK, Mølgaard H, Rasmussen BB, Thorpe S, Rose C: DNA ploidy and S-phase fraction in primary breast tumours in relation to prognostic factors and survival for premenopausal patients at high risc for recurrant disease. Acta Oncologica 27: 749-756, 1988. 71*. Geisler C, Larsen JK, Andersen E, Birgens H, Christensen BE, Drivsholm A, Hansen MM, Hokland P, Thorling K, Plesner T: The CLL2-study: preliminary results of flow cytometry immunophenotyping in the first 500 patients. Nouv Rev Fr Hematol 30: 335-337, 1988. 72*. Geisler C, Møller J, Plesner T, Dickmeiss E, Pallesen G, Larsen JK, Jacobsen N, Svejgaard A: Specific depletion of mature T lymphocytes from human bone marrow. Scand J Immmunol 29: 617-625, 1989. 73*. Lange-Vejlsgaard G, Ralfkiær E, Larsen JK, O'Connor N, Thomsen K: Fatal cutaneous T-cell lymphoma in a child with atopic dermatitis. J Amer Acad Dermatol 20: 954-958, 1989. 74*. Sunde L, Vejerslev LO, Larsen JK, Christensen IJ, Hansen HE, Mogensen B, Bolund L: Genetically different cell subpopulations in hydatidiform moles. A study of three cases by RFLP-, flow cytometric, cytogenetic, HLA- and morphologic analyses. Cancer Genet Cytogenet 37: 179-192, 1989. 75*. Svendsen LB, Larsen JK, Christensen IJ: Human skin fibroblast in vitro tetraploidy: Flow cytometric DNA assay used to confirm metaphase assay in patients with various colonic diseases. Cancer Genet Cytogenet 39: 245-252, 1989. 76*. Ralfkiaer E, Larsen JK, Christensen IJ, Thomsen K, Wantzin GL: DNA analysis by flow cytometry in cutaneous T-cell lymphomas. Brit J Dermatol 120: 597-605, 1989. 77*. Geisler C, Pallesen G, Platz P, Ødum N, Dickmeiss E, Ryder LP, Svejgaard A, Plesner T, Larsen JK, Koch C: Novel primary thymic defect with T lymphocytes expressing gamma delta T cell receptor. J Clin Pathol 42: 705-711, 1989. 78*. Ornvold K, Carstensen H, Christensen L, Larsen JK, Christensen IJ: DNA aneuploidy in sarcoid granuloma. J Clin 79*. Svendsen LB, Thorup J, Larsen JK, Nørgård T, Willumsen H, Hart Hansen O: Association betweeen tumor DNA aneuploidy and in vitro tetraploidy of skin fibroblasts in patients with colorectal neoplasms. Scand J Gastroenterol 24: 755-760, 1989. 80*. Ornvold K, Carstensen H, Larsen JK, Christensen IJ, Ralfkiaer E: Flow cytometric DNA analysis of lesions from 18 children with Langerhans cell histiocytosis (Histiocytosis X). Am J Pathol 136: 1301-1307, 1990. 81. Larsen JK: Washless double staining of a nuclear antigen (Ki-67 or bromodeoxyuridine) and DNA in unfixed nuclei. In: Flow Cytometry, Darzynkiewicz Z, Crissman HA (eds). Methods in Cell Biology 33: 227-234, Academic Press, San Diego, USA, 1990. 82. Larsen JK, Christensen IJ, Christiansen J, Mortensen BT: Washless double-staining of nuclear antigen and DNA for flow cytometry. In: Advances in Analytical Cellular Pathology, Burger G, Oberholzer M, Vooijs GP (eds), pp. 99-100, Excerpta Medica, Amsterdam, 1990. 83*. Borup-Christensen P, Erb K, Ditzel H, Nielsen B, Larsen JK, Svehag S-E, Jensenius JC: Human-human hybridoma producing monoclonal antibodies against colorectal cancer associated antigens. APMIS 98: 674-684, 1990. 84*. Svendsen LB, Thorup J, Larsen JK, Bülow S, Horn T: Correlation between in vitro tetraploidy in skin fibroblasts and development of sporadic colorectal carcinomas. Cancer Genet Cytogenet 50: 139-148, 1990. 85*. Larsen JK, Christensen IJ, Christiansen J, Mortensen BT: Washless double staining of unfixed nuclei for flow cytometric analysis of DNA and a nuclear antigen (Ki-67 or bromodeoxyuridine). Cytometry 12: 429-437, 1991. 86*. Vejerslev LO, Sunde L, Hansen BF, Larsen JK, Christensen IJ, Larsen G: Hydatidiform mole and fetus with normal karyotype: Support of a separate entity. Obstet Gynecol 77: 868-874, 1991. 87*. Geisler CH, Larsen JK, Hansen NE, Hansen MM, Christensen BE, Lund B, Nielsen H, Plesner T, Thorling K, Andersen E, Andersen PK: Prognostic importance of flow cytometric immunophenotyping of 540 consecutive patients with chronic lymphocytic leukemia. Blood 78: 1795-1802, 1991. 88. Hansen ER, Vejlsgaard GL, Larsen JK, Lisby S, Cooper KD, Thomsen K, Baadsgaard O: Immunoregulation in the skin of patients with cutaneous T cell lymphoma: Evidence for an enhanced functional capacity of CD1+ epidermal cells obtained from involved epidermis relative to uninvolved epidermis. In: Czernielewski JM (ed): Immunological and Pharmacological Aspects of Atopic and Contact Eczema. Pharmacol Skin. Karger, Basel, pp. 48-50, 1991. 89*. Carlsen NLT, Mortensen BT, Andersson PK, Larsen JK, Nielsen OH, Tommerup N: Chromosome abnormalities, cellular DNA content, oncogene amplification and growth pattern in agar culture of human neuroblastomas. Anticancer Res 11: 353-358, 1991. 90*. Carlsen NLT, Ørnvold K, Christensen IJ, Laursen H, Larsen JK: Prognostic importance of DNA flow cytometric, histopathologic and immunohistochemical parameters in neuroblastomas. Virchows Archiv A Pathol Anat 420: 411-418, 1992. 91*. Nylander K, Larsen JK, Larsen J, Clausen H, Bonding N, Dabelsteen E: The ELAM-1 ligand sialosyl-Lex is present on Langerhans cells isolated from stratified epithelium. Exp Dermatol 1: 236-241, 1992. 92. Larsen JK: Cell proliferation: Analysis by flow cytometry. Nouv Rev Fr Hematol 34: 317-335, 1992. 93*. Jensen PØ, Larsen J, Christiansen J, Larsen JK: Flow cytometric measurement of RNA synthesis using bromouridine labelling and bromodeoxyuridine antibodies. Cytometry 14: 455-458, 1993. 94*. Hansen ER, Vejlsgaard GL, Cooper KD, Heidenheim M, Larsen JK, Ho VC, Ross CW, Fox DA, Thomsen K, Baadsgaard O: Leukemic T cells from patients with cutaneous T-cell lymphoma demonstrate enhanced activation through CDw60, CD2 and CD28 relative to activation through the T-cell antigen receptor complex. J Invest Dermatol 100: 667-673, 1993. 95. Jensen PØ, Larsen JK, Christensen IJ, Christensen K, Pedersen KM, Gustavsson I: Non-disjunction events evaluated by flow cytometry in cattle and swine. In: Proceedings of 10th European Colloquium on Cytogenetics of Domestic Animals; Bosma AA (ed), pp 104-108, Utrecht University, Utrecht, The Netherlands, 1993. 96*. Strange P, Cooper KD, Hansen ER, Fisher G, Larsen JK, Fox D, Krag C, Voorhees JJ, Baadsgaard O: T- lymphocyte clones initiated from lesional psoriatic epidermis release growth factors that induce keratinocyte proliferation. J Invest Dermatol 101: 695-700, 1993. 97*. Jensen PØ, Larsen J, Larsen JK: Flow cytometric measurement of RNA synthesis based on bromouridine labelling and combined with measurement of DNA content or cell surface antigen. Acta Oncol 32: 521-524, 1993. 98. Larsen JK: Flowcytometeret - Flowcytometri med intracellulære markører. In: 1) Celledyrkning - En praktisk håndbog i dyrkning af mammale celler; Kielberg V, Brünner N, Briand P (eds), Chapters 15.1-2, Foreningen af Danske Lægestuderendes Forlag, København, 1994, pp 231-242. 2) Cellodling - En praktisk handbok i odling av mammalieceller; AB Labassco Förlag, Göteborg, 1994. 3) Celledyrkning - En praktisk håndbog i dyrkning af mammale celler, 2. uændrede udgave. Gad, København, 2001. 99. Larsen JK: Principles, capacity and limitations of immunofluorescent flow-sorting of rare cell species. In: Hematopoietic Stem Cells: The Mulhouse Manual; Wunder E, Sovalat H, Henon P, Serke S (eds). AlphaMed Press, Dayton, Ohio, U.S.A., 1994, pp 133-140. 100*. Balslev I, Christensen IJ, Rasmussen BB, Larsen JK, Lykkesfeldt AE, Thorpe SM, Rose C, Briand P, Mouridsen HT: Flow cytometric DNA ploidy defines patients with poor prognosis in node-negative breast cancer. Int J Cancer 56: 16-25, 1994. 101*. Jensen PØ, Larsen JK, Christensen IJ, van Erp PEJ: Discrimination of bromodeoxyuridine labelled and unlabelled mitotic cells in flow cytometric bromodeoxyuridine/DNA analysis. Cytometry 15: 154-161, 1994. 102*. Pedersen L, Larsen JK, Christensen IJ, Lykkesfeldt A, Holck S, Schiødt T: DNA ploidy and S-phase fraction in medullary carcinoma of the breast - A flow cytometric study using archival material. Breast Cancer Res Treat 29: 297-306, 1994. 103. Larsen JK: Measurement of cytoplasmic and nuclear antigens. In: Flow cytometry - A practical approach, 2nd edition; Ormerod MG (ed). Oxford University Press, Oxford, 1994, pp 93-117. 104*. Skouv J, Jensen PØ, Forchhammer J, Larsen JK, Lund LR: Tumor promoting phorbol ester transiently down- modulates the p53 level and blocks the cell cycle. Cell Growth & Differentiation 5: 329-340, 1994. 105. Larsen JK: 'Washless' procedures for nuclear antigen detection. In: Flow Cytometry, 2nd edition, Part A; Darzynkiewicz Z, Robinson JP, Crissman HA (eds). Methods in Cell Biology, Academic Press, San Diego, USA, Vol 41, pp 377-388, 1994. 106*. Hansen ER, Bang B, Larsen JK, Vejlsgaard GL, Baadsgaard O: In cutaneous T-cell lymphoma, class II MHC molecules on CD1+ antigen-presenting cells are upregulated in involved compared with uninvolved epidermis. Brit J Dermatol 131: 780-788, 1994. 107. Jensen PØ, Larsen JK, Christensen IJ, Christensen K, Pedersen KM, Gustavsson I: Non-disjunction events and Y Chromosome size variation evaluated by flow cytometry of sperm cells from cattle and swine. In: Proceedings of 11th European Colloquium on Cytogenetics of Domestic Animals; Christensen K (ed), Royal Vet. & Agric. University, Frederiksberg, Denmark, 1994, pp 66-70. 108. Skouv J, Lund LR, Jensen PØ, Larsen JK, Forchhammer J: p53 may be involved in the action of tumor promoters. In: Proceedings of the XVI International Cancer Congress, New Delhi, October 30 - November 5, 1994; Rao RS, Deo MG, Sanghvi LD, Mittra I (eds), Monduzzi Editore, Bologna, 1994, pp 159-163. 109*. Ottesen GL, Christensen IJ, Larsen JK, Christiansen J, Hansen B, Andersen JA: DNA analysis of in situ ductal carcinoma of the breast via flow cytometry. Cytometry (Communications in Clinical Cytometry) 22: 168-176, 1995. 110*. Ottesen GL, Christensen IJ, Larsen JK, Hansen B, Andersen JA: Flow cytometric DNA analysis of breast cancers with predominance of carcinoma in situ. A comparison of the premalignant and malignant component. Clin Cancer Res 1: 881-888, 1995. 111*. Larsen JK, Christensen IJ, Kieler J: Cell cycle perturbation by sodium butyrate in tumorigenic and non-tumorigenic human urothelial cell lines assessed by flow cytometric bromodeoxyuridine/DNA analysis. Cell Prolif 28: 359-371, 1995. 112*. Ottesen GL, Christensen IJ, Larsen JK, Kerndrup GB, Hansen B, Andersen JA: DNA aneuploidy in early breast 113*. Ottesen GL, Christensen IJ, Larsen JK, Hansen B, Andersen JA: Tissue disaggregation for flow cytometric DNA analysis: A comparison of fine-needle aspiration and an automated mechanical procedure. Cytometry (Communications in Clinical Cytometry) 26: 65-68, 1996. 114*. Larsen JK, Møller U, Christensen IJ, Christiansen J: Circadian variation of DNA replication in hamster cheek pouch epithelium analysed by tritiated thymidine labelling, flow sorting and autoradiography: No resting S phase cells in the normal epithelium. Cell Proliferation 29: 61-71, 1996. 115*. Geisler CH, Hou-Jensen K, Jensen OM, Tinggaard-Pedersen N, Hansen MM, Hansen NE, Holm M, Christensen BE, Drivsholm A, Nielsen JB, Thorling K, Andersen E, Larsen JK, Andersen PK, for the Danish CLL Study Group: The bone-marrow infiltration pattern in B-cell chronic lymphocytic leukemia is not an important prognostic factor. Eur J Haematol 57: 292-300, 1996. 116*. Ottesen GL, Christensen IJ, Larsen JK, Larsen J, Christiansen J, Baldetorp B, Linden T, Hansen B, Andersen JA: DNA ploidy analysis in breast cancer. Comparison of unfixed and fixed tissue analyzed by image and flow cytometry. Anal Quant Cytol Histol 19: 413-422, 1997. 117*. Skov L, Chan LS, Fox DA, Larsen JK, Voorhees JJ, Cooper KD, Baadsgaard O: Lesional psoriatic T cells contain the capacity to induce a T cell activation molecule CDw60 on normal keratinocytes. Am J Pathol 150: 675-683, 1997. 118*. Geisler CH, Philip P, Christensen BE, Hou-Jensen K, Pedersen NT, Jensen OM, Thorling K, Andersen E, Birgens HS, Drivsholm A, Ellegaard J, Larsen JK, Plesner T, Brown P, Andersen PK, Hansen MM: In B-cell chronic lymphocytic leukemia chromosome 17 abnormalities and not trisomy 12 are the single most important cytogenetic abnormalities for the prognosis: a cytogenetic and immunophenotypic study of 480 unselected newly diagnosed patients. Leukemia Res 21: 1011-1023, 1997. 119*. Jensen PØ, Mortensen BT, Christensen IJ, Larsen JK: Immediate bromodeoxyuridine labelling of unseparated human bone marrow cells ex vivo is superior to labelling after routine laboratory processing. Cell Prolif 31: 1-7, 1998. 120*. Sorensen M, Sehested M, Christensen IJ, Larsen JK, Jensen PB: Low-level resistance to camptothecin in a human small-cell lung cancer cell line without reduction in DNA topoisomerase I or drug-induced cleavable complex formation. Brit J Cancer 77: 2152-2161, 1998. 121*. Mortensen BT, Jensen PØ, Helledie N, Iversen PO, Ralfkiær E, Larsen JK, Madsen MT: Changing bone marrow micro-environment during development of acute myeloid leukemia in rats. Brit J Haematol 102: 458-464, 1998. 122*. Jensen AM, Lladó MB, Skov L, Hansen ER, Larsen JK, Baadsgaard O: Calcipotriol inhibits the proliferation of hyperproliferative CD29 positive keratinocytes in psoriatic epidermis in the absence of an effect on the function and number of antigen-presenting cells. Brit J Dermatol 139: 984-991, 1998. 123*. Flyger H, Larsen JK, Nielsen HJ, Christensen IJ: DNA ploidy in colorectal cancer, heterogeneity within and between tumors and relation to survival. Cytometry (Communications in Clinical Cytometry) 38: 293-300, 1999. 124*. Larsen J, Kirchhoff M, Rose H, Gerdes T, Maahr J, Lundsteen C, Larsen JK: Improved sensitivity in comparative genomic hybridization analysis of DNA heteroploid cell mixtures after pre-enrichment of subpopulations by fluorescence activated cell sorting. Anal Cell Pathol 19: 119-124, 1999. 125. Larsen JK: Measurement of cytoplasmic and nuclear antigens. In: Flow cytometry. Third edition. A practical approach; Ormerod MG (ed). Oxford University Press, Oxford, 2000, pp 133-158. 126*. Ottesen GL, Christensen IJ, Larsen JK, Larsen J, Baldetorp B, Linden T, Hansen B, Andersen J: Carcinoma in situ of the breast: correlation of histopathology to immunohistochemical markers and DNA ploidy. Breast Cancer Res Treat 60: 219-226, 2000. 127*. Andersen NS, Larsen JK, Christiansen J, Pedersen LB, Christophersen NS, Geisler CH, Jurlander J: Soluble CD40 ligand induces selective proliferation of lymphoma cells in primary mantle cell lymphoma cell cultures. Blood 96: 2219-2225, 2000. 128. Larsen JK, Jensen PØ, Larsen J: Flow cytometric analysis of RNA synthesis by detection of bromouridine incorporation. In: Current Protocols in Cytometry; Robinson JP, Darzynkiewicz Z, Dean PN, Orfao A, Rabinovitch PS, Tanke HJ, Wheeless LL (eds), John Wiley & Sons, New York, 2000, Unit 7.12, pp 1-11. 129*. Jensen PØ, Mortensen BT, Hodgkiss RJ, Iversen PO, Christensen IJ, Helledie N, Larsen JK: Increased cellular hypoxia and reduced proliferation of both normal and leukemic cells during progression of acute myeloid leukemia in rats. Cell Prolif 33: 381-395, 2000. 130. Jensen PØ, Larsen J, Larsen JK: Analysis of RNA synthesis by cytometry. In: Cytometry, Third Edition, Part B; Darzynkiewicz Z, Crissman HA, Robinson JP (eds). Methods in Cell Biology 64, Academic Press, San Diego, USA, 2001, pp 129-138. 131. Larsen JK, Landberg G, Roos G: Detection of proliferating cell nuclear antigen (PCNA). In: Cytometry, Third Edition, Part A; Darzynkiewicz Z, Crissman HA, Robinson JP (eds). Methods in Cell Biology 63, Academic Press, San Diego, USA, 2001, pp 419-431. 132*. Larsen J, Ottesen AM, Lundsteen C, Leffers H, Larsen JK: Optimization of DOP-PCR amplification of DNA for high-resolution comparative genomic hybridization analysis. Cytometry 44: 317-325, 2001. 133*. Larsen J, Ottesen AM, Kirchhoff M, Lundsteen C, Larsen JK: High resolution comparative genomic hybridization detects 7-8 megabasepair deletion in PCR amplified DNA. Anal Cell Pathol 23: 61-64, 2001. 134*. Post C, Christensen IJ, Flyger H, Christiansen J, Larsen JK: Flow cytometric bivariate analysis of DNA and cytokeratin in colorectal cancer. Anal Cell Pathol 24: 113-124, 2002. 135*. Engelholm LH, List K, Arnett SN, Cukierman E, Mitola DJ, Aaronson H, Kjøller L, Larsen JK, Yamada KM, Strickland DK, Holmbeck K, Danø K, Birkedal-Hansen H, Behrendt N, Bugge TH: uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion. J Cell Biol 160: 1009-1015, 2003. 136*. Bang B, Gniadecki R, Larsen JK, Baadsgaard O, Skov L: In vivo UVB irradiation induces clustering of Fas (CD95) on human epidermal cells. Exp Dermatol 12: 791-798, 2003. 137*. Ottesen AM, Larsen J, Gerdes T, Larsen JK, Lundsteen C, Skakkebaek NE, Rajpert-De Meyts E: Cytogenetic investigation of testicular carcinoma in situ and early seminoma by high-resolution comparative genomic hybridization analysis of subpopulations flow sorted according to DNA content. Cancer Genetics Cytogenetics 149: 89-97, 2004. 138*. Jensen CS, Lisby S, Larsen JK, Veien NK, Menné T: Characterization of Lymphocyte Subpopulations and Cytokine Profiles in Peripheral Blood of Nickel-sensitive Individuals with Systemic Contact Dermatitis after Oral Nickel Exposure. Contact Dermatitis 50: 31-38, 2004. 139*. Larsen J, Christensen K, Larsen JK, Jensen PØ, Gustavsson I, Christensen IJ: High resolution DNA flow cytometry of boar sperm cells in identification of boars carrying cytogenetic aberrations. Theriogenology 62: 501-511, 2004. 140*. Rømer MU, Due AK, Larsen JK, Hofland KF, Christensen IJ, Buhl-Jensen P, Almholt K, Nielsen OL, Brünner N, Lademann U: Indication of a role of plasminogen activator type 1 in protecting murine fibrosarcoma cells against apoptosis. Thromb Haemost 94: 859-866, 2005. 141*. Nygaard U, Larsen J, Kristensen TD, Wesenberg F, Jonsson OG, Carlsen NT, Forestier E, Kirchhoff M, Larsen JK, Schmiegelow K, Christensen IJ: Flow cytometric DNA index, G-band karyotyping, and comparative genomic hybridization in detection of high hyperdiploidy in childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol 28: 134-40, 2006. 142*. Rosenkilde MM, Benned-Jensen T, Andersen H, Holst P, Kledal TN, Lüttichau HR, Larsen JK, Geisler C, Christensen JP, Schwartz TW: Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity. J Biol Chem 281: 13199-13208, 2006. 143*. Davidsen ML, Würtz SØ, Rømer MU, Sørensen NM, Johansen SK, Christensen IJ, Larsen JK, Offenberg H, Brünner N, Lademann U: TIMP-1 gene deficiency increases tumor cell sensitivity to chemotherapy-induced apoptosis. Brit J Cancer 95: 1114-1120, 2006. 144*. Larsen AK, Lametsch R, Elce JS, Larsen JK, Thomsen B, Larsen MR, Lawson MA, Greer PA, Ertbjerg P: Genetic disruption of calpain correlates with loss of membrane blebbing and differential expression of RhoGDI-1, cofilin and tropomyosin. Biochem J 411: 657-666, 2008. 145*. Hillig T, Engelholm LH, Ingvarsen S, Madsen DH, Gårdsvoll H, Larsen JK, Ploug M, Danø K, Kjøller L, Behrendt N: A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor. J Biol Chem 283: 15217-15223, 2008. 146. Jensen PØ, Larsen J, Larsen JK: Analysis of RNA Synthesis by Cytometry. In: Essential Cytometry Methods - Reliable Lab Solutions. Darzynkiewicz Z, Robinson JP, Roederer M (eds). Elsevier/Academic Press, 2009, Chapter 34, pp 757-767. 147*. Sørensen KP, Lutterodt M, Mamsen L, Byskov AG, Larsen JK: Proliferation of germ cells and somatic cells in first trimester human embryonic gonads as indicated by S and S+G2+M phase fractions. Cell Prolif 44: 224-233, 2011.

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