CURRICULUM VITAE SILVIA LUCIA CUFFINI EDUCACIÓN
B.Sc. University of Córdoba. Argentine. 1989
Ph.D. University of Córdoba. Argentine. 1994
POSITIONS
-CONICET – Full-time Researcher (since 1997)
-Responsible Researcher of X-Ray Diffraction Sector-Radiation Laboratory CEPROCOR
(Technological Center of Cordoba) (2000-2010)
-Visited Professor in Universidade Federal de Santa Catarina (2010-2011)
PUBLICATIONS 1. “CRYSTALLOGRAPHIC, MAGNETIC AND ELECTRICAL PROPERTIES OF SOLID S.L. Cuffini, R.E. Carbonio, V.A. Macagno, A. Melo, E. Trollund and J.L. Gautier. J. Solid State Chemistry, 105 (1), 161-170 (1993). 2.“PREPARATION AND CHARATERIZATION OF SOLID SOLUTIONS SRTI(1-X)RUXO3 S.L. Cuffini and R. Carbonio. Ferroelectrics, Vol. 155, 185-170 (1994). 3. “MAGNON PAIR RAMAN SCATTERING OF SRTI(1-X) RUX O3 SOLID SOLUTIONS”
N.E. Massa, S.L. Cuffini and R. Carbonio. Ferroelectrics, Vol. 152, 319-324 (1994). 4.“SRTIO3 SINGLE CRYSTAL FIBERS GROWN BY LASER HEATED PEDESTAL
D.Reyes Ardilla, S.L. Cuffini, Y.P. Mascarenhas and A.C. Hernandes Ferroelectrics Vol. 186, pp. 141-144 (1996). . 5. “INFRARED REFLECTIVITY OF SRRUO3”
F.P. de la Cruz, N.E. Massa, S.L. Cuffini and R.E. Carbonio. Ferroelectrics Vol. 185, pp. 277-280 (1996). 6. “STRUCTURAL ANALYSIS BY RIETVELD METHOD OF POLYCRYSTALLINE CA RU
O3 AND SR RU O3 FROM ROOM TEMPERATURE UP TO 1000 OC”.
S.L. Cuffini, J.A. Guevara and Y.P. Mascarenhas. Materials Science Forum, Vols. 228-231, 789-794 (1996) 7. “CARACTERIZAÇÃO POR DRX DA ESTRUTURA PSEUDOCÚBICA DE PLZT” S.L. Cuffini, Ducinei Garcia, Y.P. Mascarenhas e J.A. Eiras. Cerâmica 277, 633 - 636 (1996). 8.“LASER HEATED PEDESTAL GROWTH OF SR2RUO4 SINGLE CRYSTAL FIBERS
D.Reyes Ardilla, M.R.B. Andreeta, S.L. Cuffini, A.C. Hernandes, J.P. Andreeta and Y.P. J. Crystal Growth, 177 (1-2), 52-56 (1997) 9. “SPECIFIC HEAT MEASUREMENT OF THE MAGNETORESISTANT PEROVSKITE
F. Castelpoggi, L. Morelli, H.R. Salva, S.L. Cuffini, R.E. Carbonio and R.D. Sanchez. Solid State Comm. 101, (8), 597-599 (1997). 10. “HIGH TEMPERATURE STUDIES OF PEROVSKITE OXIDES: X-RAY DIFFRACTION S.L. Cuffini, J.A. Guevara, Y.P. Mascarenhas, P. de la Presa, A. Ayala and A. López Ceramica 43 (280) 91, Mar/Abr (1997) 11. “THE STRUCTURE OF ORTHORHOMBIC HAFNIATES BY NEUTRON POWDER
J.A. Guevara, S.L. Cuffini, Y.P. Mascarenhas, R.E. Carbonio, J.A. Alonso, M.T.
Fernandez, P. de la Presa, A. Ayala and A. López Garcia.
Materials Science Forum, 278-281, 720 (1998) 12. “SINGLE “CRYSTAL SRTIO3 FIBER GROWN BY LASER HEATED PEDESTAL
GROWTH: INFLUENCE OF THE CERAMIC FEED ROD PREPARATION IN THE FIBER
D.Reyes Ardilla, M.R.B. Andreeta, S.L. Cuffini, A.C. Hernandes, J.P. Andreeta and Y.P. Materials Research, Vol. 1, N01, 11-17 (1998) 13 “LASER HEATED PEDESTAL GROWTH OF ORTHORHOMBIC SRHFO3 SINGLE
D.Reyes Ardilla, M.R.B. Andreeta, A.C. Hernandes, , S.L. Cuffini , J.A. Guevara and Y.P. J. Crystal Growth 200 (1999) 621-624 14. “PHONON ACTIVITY UPON REDUCING ARUO3-Ô (A = CA, SR)”
N.E. Massa, S.L. Cuffini, V. Nassif , R.E. Carbonio and H. Salva Physica Status Solidi(B) 220, 603 (2000) 15.“ELECTRICAL CONDUCTIVITY SRTI(1-X)RUXO3”
R.F. Bianchi, J.A.G. Carrió, S.L. Cuffini, Y.P. Mascarenhas, R.M. Faria. Phys. Rev. B Vol. 62, N 16, 10785-10789 (2000) 16.¨ELECTRONIC STRUCTURE AND METAL-INSULATOR TRANSITION IN SRTI(1-X)
M. Abbate, J.A. Guevara, S.L. Cuffini, Y.P. Mascarenhas and E. Morikawa European Physical Journal B 25, 203-208 (2002). 17. THE STALING OF BREAD: X-RAY DIFFRACTION
Pablo Ribotta, S.L. Cuffini and Alberto E. León European Food Research and Technology Vol. 218 Nº 3, 219-223 (2003) 19. PHOTOEMISSION SPECTRA AND BAND STRUCTURE CALCULATION OF Ca(1-X) Physica B – Condensed Matter 354(1-4): 39-42 (2004) 19. PHOTOEMISSION SPECTRA AND BAND STRUCTURE CALCULATION OF Ca(1-X) Physica B – Condensed Matter 354(1-4): 39-42 (2004) 20. X-RAY FLUORESCENCE ANALYSIS APPLIED TO GEOCHEMISTRY OF QUARTZ
D. Pérez1, M. Rubio1, A. Bonalumi2,3, J. Sfragulla2,3, A. López1, A. Guereschi3, C.
Vazquez4, M. Gozalvez1, M. Luchesi1, R.G. Badini1, S.L. Cuffini1, G. Sphan1, M. Inga1, A. X-Ray Spectroscopy 34(1): 59-63 (2005)
S.C. Pérez, L. Cerioni, A.E. Wolfenson, S. Faudone and S.L. Cuffini,
International Journal of Pharamceuticals 298 143–152 (2005). 22. SOLID-STATE STUDIES OF 2-HYDROXY-N-[3(5)-PYRAZOLYL]-1,4-
N. R. Sperandeo,1* A. Karlsson,2 S.L. Cuffini,3 S. Pagola4 and P.W. Stephens4
AAPS PharmaSciTech 2005, vol 6 (4) art. 82, (pdf pag 655-663). Pharm Biomed Anal. 2006 Nov 30; : 17141446 24. NINE N-ARYL-2-CHLORONICOTINAMIDES: SUPRAMOLECULAR STRUCTURES IN
Cuffini, Silvia; Glidewell, Christopher; Low, John N.; de Oliveira, Aline G.; de Souza,
Marcus V. N.; Vasconcelos Thatyana R. A.; Wardell, Solange M. S. V. ;Wardell, James L.
Acta Crystallographica B 62,Part 4, pages 651-665 (2006) 25. POLIMORFISMO Y SU IMPACTO EN LA BIODISPONIBILIDAD: PARTE I Boletín del Sistema de Unificado de Farmacovigilancia de la Provincia de Córdoba (SURF). Año 2 Número 5. Octubre 2006. Pag. 2-8 26. VIBRATIONAL SPECTRUM AND QUANTUM MECHANICAL CALCULATIONS IN
A. P. Ayala, H. W. Siesler, S.M.S.V. Wardell N. Boechet, V. Dabbene and S. L. Cuffini.
Journal of Molecular Structure 828 (2007) 201-210. 27. PHYSICOCHEMICAL CHARACTERIZATION OF DEFLAZACORT: THERMAL
ANALYSIS, CRYSTALLOGRAPHIC AND SPECTROSCOPIC STUDY
Silvia L. Cuffini,[a] Javier Ellena,[b] Yvonne P. Mascarenhas,[b] Alejandro P. Ayala,[c] Heinz
W. Sielser,[d] Josué Mendes Filho,[c] Gustavo A. Monti,[e] Virginia Aiassa[f] and Norma R.
Steroids 72 (3), 261-269 (2007) 28. POLIMORFISMO Y SU IMPACTO EN LA BIODISPONIBILIDAD: PARTE II Boletín del Sistema de Unificado de Farmacovigilancia de la Provincia de Córdoba (SURF). Año 2 Número 7. Octubre 2007. Pag. 4-6 29. LOW-TEMPERATURE STUDY OF A NEW NEVIRAPINE PSEUDOPOLYMORPH
C.C.P. da Silva, S.L. Cuffini, S.N. Faudone, A.P. Ayala, J. Ellena
Acta Cryst. E (2008) E 64, o292 30. ROSIGLITAZONE MALEATE 0.25-HYDRATE: A PSEUDOPOLYMORPHIC FORM Acta Cryst. (2008). C64, o119-o122 31. SYNTHESIS AND CHARACTERIZATION OF A NEW MEBENDAZOLE SALT:
E.V. Brusau, G.E. Cami´, G.E. Narda, S. Cuffini, A.P. Ayala, J. Ellena
Journal of Pharmaceutical Sciences, Vol. 97, no. 1, January 2008, 542-552. 32. (S)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1H-3,1-
Silvia Cuffini, R. Alan Howie, Edward R. T. Tiekink, James L. Wardell and
Acta Cryst. (2009). E65, o3170–o3171 33. POLYISOPRENE MATRIX FOR PROGESTERONE RELEASE: IN VITRO AND IN
V. Herediaa, I.D. Biancoa, H. Tríbulod, R. Tríbulod, M. Ferro Seoane, S. Faudonea, S.L.
Cuffinia, N.A. Demichelis, H. Schalliol , D.M. Beltramoa
International Journal of Pharmaceutics 382 (2009) 98–103 34. CRYSTALLOGRAPHIC, THERMAL AND SPECTROSCOPIC CHARACTERIZATION
OF A CIPROFLOXACIN SACCHARINATE POLYMORPH
C.B. Romañuk, Y. Garro Linck, A.K. Chattah, G.A. Monti, S.L. Cuffini, M.T. Garland, R.
International Journal of Pharmaceutics 391 (2010) 197–202 MEETING PRESENTATIONS Nacional Meetings (55) Internacional Meetings (40)
POLIMORFOS CRISTALINOS DEL SULFATO DE R-SALBUTAMOL, PROCEDIMIENTOS
PARA SU OBTENCIÓN Y COMPOSICIONES FARMACÉUTICAS QUE LOS
(R-Salbutamol Sulfate polymorphs. Preparation methods and pharmaceutical formulations)
INPI (Argentina - 16/08/05, Nº P050103458.) BOOK CHAPTERS -Difracción y Espectroscopias de Rayos X. .
Introducción a la Electrocerámica (ISBN 84-7402-305-X) Madrid 2003.
3- Polymorphism in Drugs
Silvia L. Cuffini, Altivo Pitaluga Jr. and Dora Tombari
Ed. Profa. Dra. Silvia Storpirtis
Biopharmacotechnique (ISBN 978-85-277-1587-4) Rio de Janeiro. 2009.
THESIS ADVISOR
2009- Mag. Thesis. S.N. Faudone- University of Córdoba. Argentina.
2008-Ph.D. Thesis M.R. Ceballos-University of Córdoba. Argentina.
THESIS Co-ADVISOR
1998- Ph. D Thesis. J.A.G.Carrio-University of Sao Paulo. Brazil (Advisor: Y.P.
Mascarenhas, Co-Advisor: Silvia Cuffini)
2004- Master Thesis. Márcia de Windson Caetano - University Federal of Ceará- Brazil.
(Advisor: Alejandro Pedro Ayala, Co-Advisor: Silvia Cuffini)
2005- Ph.D Thesis. Sara Braga Honorato. University Federal of Ceará- Brazil. (Advisor:
Alejandro Pedro Ayala, Co-Advisor: Silvia Cuffini)
PARTICIPATION IN INTERNATIONAL COOPERATION PROJECTS -Argentina-Brazil Co-operation (Brazilian Agency) (1997) -Argentina-France Co-operation (SECYT-ECOS) (1997-1999) -Argentina-Spain Co-operation (RED CYTED) (1998-2001) -Argentina-Brazil Co-operation (CICAL) (2004) -Argentina-Brazil Co-operation (CAPES-SECYT) (2005-2006) -Argentina-Brazil Co-operation (UNESCO) (2005-2006) -Argentina-Brasil Co-operation PROSUL (2007-2010) OTHER ACTIVITIES -Secretary of Argentine Association of Crystallography (AACr) -Advisor in Polymorphism in pharmaceutical drugs PATENTS – INPI Brazil, -Advisor in Solid State Chemistry of drugs - Pharmaceutical Laboratories in Argentina and Brazil - Coordinator and Local Organizer: meetings, courses, lab. certifications -ICDD-WORKSHOP Advanced Methods in X-ray Powder Diffraction (2001) -Course SOLID STATE CHARACTERISATION OF PHARMACEUTICAL DRUGS. Prof. Dr. Raj Suryanarayanan (2001) -SARX 2002 ( Latin-American Symposium in X-ray Analytical Techniques) (2002) -ICDD-WORKSHOP during SARX 2004
-ISO 9001 (version 2000) Certification of X-ray Laboratory – LRA CEPROCOR (March 2004) (Responsible Researcher)
Specialist Packages Description Discount illnesses like heart disease, diabetes and screens for such illnesses like prostate cancer in males and ovarian and breast cancers in female. The Raffles Executive recommended for people age 40 years old and above. ( refer to annex 1) package comprising all the component of the executive package with added endoscopic photography and audio