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In case of emergency call 3E at 800.451.8346 MATERIAL SAFETY DATA SHEET: AMPICILLIN, SODIUM SALT CATALOG NUMBER: AB00115 SECTION I - CHEMICAL IDENTIFICATION NAME: AMPICILLIN SODIUM SALT SECTION II - COMPOSITION/INFORMATION ON INGREDIENTS CAS: 69-52-3 MF: C16H18N3NAO4S ALPEN-N * AMCILL-S * D(-)-ALPHA-AMINOBENZYLPENICILLIN SODIUM SALT * AMPICILLIN SODIUM * AMPICILLIN SODIUM SALT * BINOTAL SODIUM * CITTERAL * DOMICILLIN * OMNIPEN-N * PEN A/N * PENBRITIN-S * PENIALMEN * POLYCILLIN-N * PRINCIPEN/N * SODIUM D-(-)-ALPHA- AMINOBENZYLPENICILLIN * SODIUM AMIPICILLIN * SODIUM BINOTAL * SODIUM P-50 * SECTION III - HAZARDS IDENTIFICATION LABEL PRECAUTIONARY STATEMENTS HARMFUL MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT. TARGET ORGAN(S): BLOOD DO NOT BREATHE VAPOR SPRAY. WEAR SUITABLE. PROTECTIVE CLOTHING. SECTION IV - FIRST-AID MEASURES IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER. IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE REUSE. SECTION V - FIRE FIGHTING MEASURES EXTINGUISHING MEDIA WATER SPRAY. CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM. SPECIAL FIREFIGHTING PROCEDURES WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES. UNUSUAL FIRE AND EXPLOSIONS HAZARDS EMITS TOXIC FUMES UNDER FIRE CONDITIONS. SECTION VI - ACCIDENTAL RELEASE MEASURES WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE. SECTION VII - HANDLING AND STORAGE REFER TO SECTION 8. SECTION VIII - EXPOSURE CONTROLS/PERSONAL PROTECTION WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING. USE ONLY IN A CHEMICAL FUME HOOD. SAFETY SHOWER AND EYE BATH. DO NOT BREATHE DUST. DO NOT GET IN EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE. WASH THOROUGHLY AFTER HANDLING. KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE. SECTION IX - PHYSICAL AND CHEMICAL PROPERTIES APPEARANCE AND ODOR SOLID. PHYSICAL PROPERTIES MELTING POINT: 215 C (DEC) SECTION X - STABILITY AND REACTIVITY INCOMPATIBILITIES STRONG OXIDIZING AGENTS HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS TOXIC FUMES OF: CARBON MONOXIDE, CARBON DIOXIDE NITROGEN OXIDES SULFUR OXIDES SECTION XI - TOXICOLOGICAL INFORMATION ACUTE EFFECTS MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION. MAY CAUSE SKIN IRRITATION. MAY CAUSE EYE IRRITATION. MATERIAL MAY BE IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY TRACT. MAY CAUSE ALLERGIC REACTION. TARGET ORGAN(S): BLOOD CHRONIC EFFECTS THIS PRODUCT IS OR CONTAINS A COMPONENT THAT IS NOT CLASSIFIABLE AS TO ITS CARCINOGENICITY BASED ON ITS IARC, ACGIH, NTP OR EPA CLASSIFICATION. TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED. ADDITIONAL INFORMATION WARNING:THERE ARE REPORTS OF SERIOUS AND SOMETIMES FATAL HYPERSENSITIVITY (ANAPHYLACTIC) REACTIONS OCCURRING IN PEOPLE RECEIVING PENCILLIN THERAPY BY THE PARENTERAL ROUTE ALTHOUGH IT HAS ALSO OCCURRED VIA ORAL ADMINISTRATION. THESE REACTIONS USUALLY OCCUR IN INDIVIDUALS WHO HAVE A HISTORY OF SENSITIVITY TO MULTIPLE ALLERGENS, ASTHMA, HAY FEVER OR URTICARIA. INGESTION HAS RESULTED IN NAUSEA, VOMITING, DIARRHEA, GLOSSITIS, STOMATITIS, ENTEROCOLITIS, PSEUDOMEMBRANOUS COLITIS. HYPERSENSITIVITY REACTIONS: ERYTHEMATOUS MACULOPAPULAR RASHES, ERYTHEMA MULTIFORME, URTICARIA AND EXFOLIATIVE DERMATITIS. RTECS #: XH8400000 4-THIA-1-AZABICYCLO(3.2.0) HEPTANE-2-CARBOXYLIC ACID, 6-(2-AMINO-2-PHENYLACETAMIDO)- 3,3-DIMETHYL-7- OXO-, SODIUM SALT, D-(-)- TOXICITY DATA ORL-RAT LD50:>5314 MG/KG BJPCAL 18,356,1962 IPR-RAT LD50:7400 MG/KG TXAPA9 18,185,1971 SCU-RAT LD50:>5314 MG/KG BJPCAL 18,356,1962 ORL-MUS LD50:>5314 MG/KG BJPCAL 18,356,1962 IPR-MUS LD50:5700 MG/KG TXAPA9 18,185,1971 SCU-MUS LD50:>5314 MG/KG BJPCAL 18,356,1962 TARGET ORGAN DATA GASTROINTESTINAL (HYPERMOTILITY, DIARRHEA) GASTROINTESTINAL (OTHER CHANGES) ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE INFORMATION. SECTION XII - ECOLOGICAL INFORMATION DATA NOT YET AVAILABLE. SECTION XIII - DISPOSAL CONSIDERATIONS DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A CHEMICAL, INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS. SECTION XIII - REGULATORY INFORMATION EUROPEAN INFORMATION: HARMFUL R 42/43 MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT. S 23 DO NOT BREATHE VAPOR SPRAY. S 36 WEAR SUITABLE PROTECTIVE CLOTHING. REVIEWS, STANDARDS, AND REGULATIONS: OEL=MAK IARC CANCER REVIEW:ANIMAL LIMITED EVIDENCE IMEMDT 50,153,1990 IARC CANCER REVIEW:HUMAN INADEQUATE EVIDENCE IMEMDT 50,153,1990 IARC CANCER REVIEW:GROUP 3 IMEMDT 50,153,1990 NOES 1983: HZD X3564; NIS 2; TNF 549; NOS 8; TNE 23006; TFE 18439 REVISION DATE 4/8/04

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