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American Endurance Ride Conference
Rule 13 Appendices
Revised December 1, 2013, for the 2014 AERC ride season.
Appendix A. Prohibited Substances
Acepromazine . Atrovet, Notensil, PromAce® Benazeprilat, Benazepril and MC-tab .Lotrel, Acetaminophen (Paracetamol) .Tylenol, Tempra, etc.
Carticaine (see articaine) . Septocaine; Cathinone (khat, kat, qat, quat, chat, catha, Albuterol (Salbutamol) .Proventil, Ventolin Chloral hydrate . Nactec, Oridrate, etc. Aminoglycosides . Gentocin, Amiglyde, Tobrex, amikacin, tobramycin, neomycin, spectinomycin Diclofenac . Surpass, Voltaren, Voltarol Butabarbital (Secbutobarbitone) . Butacaps, Butamben (butyl aminobenzoate) . Butesin Articaine .Septocaine; Ultracaine, etc.
Azaperone . Stresnil, Suicalm, Fentaz (with Droperidol .Inapsine, Droleptan, Innovar-Vet A. Prohibited Substances . . .
Fluphenazine .Prolixin, Permitil, Anatensol, etc. Enalapril (metabolite enaloprilat) .Vasotec Methotrimeprazine .Levoprome, Neurocil, etc. Fluvoxamine . Dumirox, Faverin, etc.
Fosinopril, metabolite, Fosinoprilat .Monopril Levothyroxine . Eltroxin, Synthroid, Soloxine, Erythropoietin (EPO) .Epogen, Procrit, etc. Gamma-oryzanol (other than naturally occurs in equine feeds such as rice bran/rice bran oil) Guaifenesin (glycerol guiacolate) . Gecolate Macrolides . Zithromax, Biaxxin (including Ethylaminobenzoate (Benzocaine) .Semets, etc. erythromycin, azithromycin, clarithromycin) purpose of and at the levels of providing a calming/tranquilizing effect. Magnesium Hemoglobin glutamers .Oxyglobin Hemopure Moexipril (metabolite, moexiprilat) .Uniretic Hydrocortisone (Cortisol) . Cortef, etc.
Nabumetone .Anthraxan, Relafen, Reliflex Fenspiride . Respiride, Respan, etc.
Imipramine . Imavate, Presamine, Tofranil Mephobarbital (Methylphenobarbital) Mebaral Nandrolone .Nandrolin, Laurabolin, Durabolin Flunitrazepam . Rohypnol, Narcozep, Darkene, Fluoroquinolones . Baytril, Cipro, Ciloxan, A180 Ketazolam .Anxon, Laftram, Solatran, Loftran A. Prohibited Substances . . .
Omeprozole.Gastroguard, Ulcerguard, Prilosec, Trandolapril (and metabolite, trandolaprilat) Spirapril, metabolite Spiraprilat . Renomax Succinylcholine . Sucostrin, Quelin, etc. Sulfonamides and Potentiated Sulfonamides .
Tribrissen, Septra, TMS (sulfamethazine, (including procaine penicillin G, sodium or Yucca other than as a feed additive for the Quinapril, metabolite Quinaprilat . Accupril Ramipril, metabolite Ramiprilat . Altace Appendix B. Categories of Prohibited Substances
1. Anti-inflammatory drugs (steroidal and/or non- 12. Hormonal products (natural or synthesized) ex- steroidal) or other substances that have similar phar- cept for progesterone or similar acting progestagens in mares only, administered for the purpose of con- 2. Antipsychotic, anti-epilectic and antihypertensive 25. Bronchodialators and products used for the 13. Pharmacological substances designed and mar- treatment of recurrent airway disease, mucolytics and 3. Antidepressants such as selective serotonin reup- keted primarily for human use or use in other species take inhibitors, monoamine oxidase inhibitors and and for which alternative and generally accepted 4. Tranquilizers and sedatives including benzodiaz- 14. Hypersensitizing or desensitizing agents 30. Topical agents, including ophthalmic, otic, der- mal and wound ointments or liniments that contain 7. Amphetamines and other central nervous system stimulants including cocaine and related psychotic drugs 19. Proton pump inhibitors and H2 receptor antago- 31. Any substance administered while competing in an endurance ride by nasogastric tube or syringe/ 10. Anabolic steroids and growth promoters 21. Substances designed, marketed, and/or admin- 32. Yucca administered for the purpose of and at 11. Peptides and genetically recombinant substanc- istered to affect the behavior of an equine in a calm- the levels of ammonia reduction and intestinal health. es such as erythropoietin, insulin growth factor and ing (tranquilizing) or energizing (stimulating) manner. Yucca administered for any other purpose or at levels This is to include herbal and/or natural products.
to provide anti-inflammatory effect is prohibited.
Appendix C. Allowed Substances
1. Vitamins (other than thiamine administered for the as altrenogest (Regumate) only in mares to control purpose of providing a calming/tranquilizing effect) 12. Magnesium sulphate admistered for the purpose 8. The following chondroprotective agents: glucos- of electrolyte supplementation. Magnesium sulphate amine, chondroitin sulfate, polysulfated glycosami- administered for the purpose of and at the levels of 4. Topical agents such as liniments and wound dressings noglycan, hyaluronate. Not to be administered by providing a calming/tranquilizing effect is prohibited.
that do not contain a prohibited substance needle/syringe while competing in an endurance ride 9. Acid neutralizers including aluminum hydroxide 6. Ice and ice water administered orally and/or topi- *There is insufficient information available to advise as to the timing of administration close to the time 7. Progesterone and similar acting progestagens such Appendix D. Threshhold Levels
Urinary thresholds refer to the parent drug and/or metabolite. S = stallions, G = geldings, M = mares) (epitestosterone) . 20 ng/ml (G) . urine *The threshold for furosemide applies only if the urine Dimethylsulfoxide (DMSO) . 15,000 ng/ml . urine specific gravity is less than 1.010.
Appendix E. Known Detection Times for Substances Used Therapeutically in the Horse
Typical Dose/Route* for
Elimination Detection Limit
Drug (Brand Name)
Therapeutic Indication
1000 lb. (450kg) Horse
Half-Life
Source of Info.
____________________________________________________________________________________________________________________________________________________________
Tranquilizers/Sedatives
____________________________________________________________________________________________________________________________________________________________acepromazine (Atravet®, PromAce®) Tranquilizer used for calming horses. Has no pain-relieving action. ____________________________________________________________________________________________________________________________________________________________butorphanol (Torbugesic®) Sedative with pain-relieving action, used frequently to treat colic in horses. ____________________________________________________________________________________________________________________________________________________________dantrolene (Dantrium®) Muscle relaxant used in horses with myopathies (“tying-up”). ____________________________________________________________________________________________________________________________________________________________detomidine (Dormosedan®) Sedative with pain-relieving action, used frequently to treat colic in horses. ____________________________________________________________________________________________________________________________________________________________guaifenesin (Guailaxin®, Gecolate®) Muscle relaxant used in horses with myopathies (“tying-up”). ____________________________________________________________________________________________________________________________________________________________methocarbamol (Robaxin®) Muscle relaxant used in horses with myopathies (“tying-up”). ____________________________________________________________________________________________________________________________________________________________romifidine (Sedivet®) Sedative with pain-relieving action, used frequently to treat colic in horses. ____________________________________________________________________________________________________________________________________________________________
Anti-inflammatories/Pain Relievers
____________________________________________________________________________________________________________________________________________________________aspirin Orally or pain-reliever in the horse. Sometimes used to treat periodic ophthalmia 11.7 grams Oral y (“moon blindness”), laminitis, and colic due to parasite damage.
____________________________________________________________________________________________________________________________________________________________diclofenac sodium (Surpass) Applied topically as an anti-inflammatory agent. ____________________________________________________________________________________________________________________________________________________________dimethylsulfoxide (DMSO) Applied topically as an anti-inflammatory agent, given IV to treat myopathies 19.8 grams topically ____________________________________________________________________________________________________________________________________________________________flunixin meglumine (Banamine®) Nonsteroidal anti-inflammatory drug used to treat colic and ____________________________________________________________________________________________________________________________________________________________ketoprofen (Ketofen®, Anafen®) Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation ____________________________________________________________________________________________________________________________________________________________lidocaine (Xylocaine®) ____________________________________________________________________________________________________________________________________________________________meclofenamic acid (Arquel®) Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation.
____________________________________________________________________________________________________________________________________________________________mepivicaine (Carbocaine®) ____________________________________________________________________________________________________________________________________________________________naproxen (Equiproxen, Aleeve®) Nonsteroidal anti-inflammatory drug used to treat colic and musculoskeletal pain and inflammation.
____________________________________________________________________________________________________________________________________________________________phenylbutazone (“Bute”) Nonsteroidal anti-inflammatory drug used to treat colic and ____________________________________________________________________________________________________________________________________________________________procaine (Novocaine®) ____________________________________________________________________________________________________________________________________________________________procaine penicillin G Combined with penicillin to make the antibiotic slowly absorbed from the injection site, to give it a long duration of antibacterial action. ____________________________________________________________________________________________________________________________________________________________
Corticosteroids
____________________________________________________________________________________________________________________________________________________________betamethasone (Betasone®, Celestone®) Anti-inflammatory; allergic reactions. ____________________________________________________________________________________________________________________________________________________________dexamethasone (Azium®) ____________________________________________________________________________________________________________________________________________________________flumethasone (Flucort®) ____________________________________________________________________________________________________________________________________________________________isoflupredone (Predef 2X®) ____________________________________________________________________________________________________________________________________________________________methylprednisolone acetate ____________________________________________________________________________________________________________________________________________________________prednisolone ____________________________________________________________________________________________________________________________________________________________prednisone ____________________________________________________________________________________________________________________________________________________________triamcinolone (Vetalog®) ____________________________________________________________________________________________________________________________________________________________
Miscellaneous Drugs
____________________________________________________________________________________________________________________________________________________________aminophylline Opens airways in horses with “heaves”. ____________________________________________________________________________________________________________________________________________________________clenbuterol (Ventipulmin®) Opens airways in horses with “heaves”. ____________________________________________________________________________________________________________________________________________________________dembrexine (Sputolysin®) Expectorant for horses with “heaves”. ____________________________________________________________________________________________________________________________________________________________diphenhydramine (Benadryl®) ____________________________________________________________________________________________________________________________________________________________isoxuprine (Vasodilan®) Dilates blood vessels, used for treatment of navicular disease. ____________________________________________________________________________________________________________________________________________________________omeprazole (Gastrogard®, Ulcergard®) Proton pum inhibitor used for the treatment of esophagitis, erosive ____________________________________________________________________________________________________________________________________________________________theophylline Opens airways in horses with “heaves”. ____________________________________________________________________________________________________________________________________________________________* IV - intravenous, IM - Intramuscular, SC - Subcutaneous, IA - Intra-articular (into the joint); ** No information available.
Appendix F. Prohibited Treatments
1. Acupuncture, or any procedure involving the Appendix G item 4) for the purpose of administer- points. This would include but not be limited to insertion of a needle into the equine.
ing a substance or to stimulate a response.
2. Osseous manipulation (chiropractic).
5. Extracorporeal Shockwave therapy or similar 7. Administration of a local anesthetic, either 3. Any manipulative procedure using an ex- device to produce a temporary or permanent topical, injectable or oral to any part of the horse ternal device or instrument such as devices to analgesia. This would also include radiofrequency or any procedure that results in desensitization manipulate or stimulate acupressure or response (RF) neurectomy. Extracorporeal shockwave points, including but not limited to bioscans, laser therapy is not permitted within 7 days of com- 8. Pinfiring/pinfreezing – visible active, open lesions from such a procedure would prohibit a 4. Any procedure involving the placement of a 6. Any external magnetic field device or tube or other instrument into the equine (other electropulse generator device applied either 9. The use of substances or devices that cool than the oral cavity using a dosing syringe, see over the entire body or specifically on pressure Appendix G. Allowable Treatments
1. Massage, deep massage/acupressure using digital (hand/finger) pres- ice water. The use of devices or substances that cool below 0 degrees 2. The use of instruments commonly know as grooming instruments.
4. The oral administration of permitted substances by means of dosing 3. The use of ice boots and other means of applying ice/ice water topically. Can include the use of compression wraps as well as devices that circulate 5. Healed scars from pinfiring are allowed.

Source: http://www.aerc.org/DrugRuleAppendices.pdf