World Headquarters Phone: 202.965.2288 1000 Potomac St., NW•Suite 151 Fax: 202.965.0044 Washington, DC 20007 www.RxBioSci.com •London One Northumberland Avenue Trafalgar Square London WC2N 5BW
Washington, DC – May 8, 2007 a specialty pharmaceutical
company, is pleased to announce that it has secured the global exclusive rights to
•Hong Kong
MucoAd™, a mucoadhesive pharmaceutical agent that can be “loaded” with nearly any
pharmaceutical preparation and delivered to a variety of mucosal tissues.
Suites 2207-2209 Tower Two, Lippo Centre 89 Queensway, Admiralty
MucoAd™ is a patented non-toxic, non-irritating, liquid polymer mucoadhesive carrier
Hong Kong
that prolongs the contact time between drug and mucosa, thus increasing bioavailability
and efficacy of the delivered drug. The adherence of pharmaceuticals to the mucosa
may permit lower doses of the administered drug so that the desired therapeutic affect
could be achieved with fewer adverse reactions.
The MucoAd™ technology is versatile. It can be applied to powders, gels, microspheres,
liposomes, and liquid formulations. It is currently being tested for intranasal
applications, and other sites of application include sublingual, ophthalmic, vaginal, and
rectal. Potential transmucosal derivatives in discussion include nasal decongestants,
second-generation antihistamines, second-generation H1-antagonists, topical
corticosteroids, CNS drugs, anti-emetics, anti-infectives, cold & cough preparations,
asthma medications, vascular products, periodontal products, , and topical agents for
The company is now developing the methods and technology to assess and adjust the
required mucoadhesive properties for several specific medications. Thus far,
researchers have shown that using MucoAd™ with a decongestant preparation of
xylometazoline 0.1% increased clinical efficacy as compared to the standard
decongestant spray while also decreasing rebound swelling and other side effects.
MucoAd™ is also being used to develop a stable intranasal solution of the antihistamine
loratadine, commonly known as Claritin® or Alavert®, which formerly was practically
insoluble. A topical nasal formulation of the anti-emetic agent clopramide is also in
Christos S. Efessiou, Strategic BioSciences Chief Executive Officer, commented
“MucoAd™ represents the New Frontier in drug delivery because it enables the
administration of a nearly limitless number of pharmaceutical products via a safe and
effective route. More importantly, as MucoAd™ bypasses the digestive tract and liver, it
slows deactivation and reduces common irritating GI side effects associated with many
oral medications. We are excited at the possibilities MucoAd™ offers in the
administration of medications which up to now could only be delivered by injection such
Neil White, Director of Fortune Apex Development said “Strategic BioSciences
represents a significant step towards developing the applications, for our unique,
patented technology, which in addition to clinical advantages, offers MucoAd™
licensees significant opportunities for patent extensions.”
Strategic Pharmaceuticals Company, doing business as, is a
District of Columbia based pharmaceutical company. It is the joint venture of SRxA
Holdings Inc, an affiliate of of Washington, DC and
of Hong Kong, The licensing agreement granting Strategic
BioSciences the exclusive global rights to MucoAd™, was recently signed in Seoul, Korea.
VAN DOORSLAER , PHILIPPE M. HEYNDERICKX , JO1KERMIT, Department of Applied Mathematics, Biometrics and ProcessControl, Faculty of Bioscience Engineering, Ghent University, Coupure links 653,2EnVOC, Department of Sustainable Organic Chemistry and Technology, Facultyof Bioscience Engineering, Ghent University, Coupure links 653, B-9000 Ghent,Cellular automata (CA) appeared for the first time in
Depressing researchIt is hard to imagine the anguish experienced by theeasily manipulated by those with potentially massiveparents, relatives, and friends of a child who hastaken his or her own life. That such an event couldGlaxoSmithKline SSRI paroxetine, for example,be precipitated by a supposedly beneficial drug is aamounted to US$4·97 billion last year alone. catastrophe. The idea of t