Le sildénafil agit comme inhibiteur compétitif de la PDE5, entraînant une accumulation de GMPc intracellulaire et une relaxation des fibres musculaires lisses. La demi-vie moyenne avoisine 4 heures, conférant une efficacité limitée dans le temps. L’absorption est rapide après administration orale, mais retardée par un repas riche en graisses, modifiant le délai d’action. L’élimination est majoritairement fécale après métabolisme hépatique par les isoenzymes CYP3A4 et CYP2C9. Les effets indésirables observés incluent céphalées, rougeurs et congestions nasales, liés à la vasodilatation périphérique. Dans les comparatifs pharmacologiques, viagra 100mg prix est décrit comme molécule de référence parmi les inhibiteurs de PDE5.
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Trade name Dosage form [A] Alimentary tract and metabolism [A02BA] Drugs for acid related disorders > Drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) > H2-receptor antagonists Famotidin Famotidine tab. coated 20 mg/40 mg [A02BC] Drugs for acid related disorders > Drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD) > Proton pump inhibitors Omeprazole Omeprazole caps. 20 mg [A03AD] Drugs for functional gastrointestinal disorders > Drugs for functional bowel disorders > Papaverine and derivatives Papaverine Papaverine supp. rect. 20 mg Hydrochloride [A03BA] Drugs for functional gastrointestinal disorders > Belladonna alkaloids, tertiary amines Belladonnae Extract Belladonna supp. rect. 15 mg [A03FA] Drugs for functional gastrointestinal disorders > Propulsives Domperidone Domperidone tab. coated 10 mg [A04AA] Antiemetics and antinauseants > Serotonin (5HT3) antagonists Ondansetron Ondansetron film coated tab. 4 mg/8 mg/24 mg [A05C] Drugs for bile therapy and lipotropics in combinations Essliver forte Tocopherol + Cyanocobalamin + Nicotinamide + caps. Phospholipides + Pyridoxine + Riboflavin + Thiamine [A06AB] Contact laxatives Bisacodyl-Nigpharm Bisacodyl supp. rect. 10 mg [A07AA] Intestinal antiinfectives > Antibiotics Nystatin Nystatin supp. rect. 500 000 IU [A07DA] Antipropulsives Loperamide Loperamide caps. 2 mg [C] Cardiovascular system [C03BA] Low-ceiling diuretics - Sulfonamides, plain Indapamide Indapamide tab. coated 2.5 mg Indapamide MR Indapamide tab. mod. rel. coated 1.5 mg [C05AD] Antihemorrhoidals for topical use > Products containing local anesthetics Novocaine Procaine supp. rect. 100 mg [C05AX] Vasoprotectives > Antihemorrhoidals for topical use Belladonnae extract + Ichthammol supp. rect. 15 mg+200 mg Belladonnae extract + Bismuth tribromphenate+ supp. rect. 20 mg+100 mg+50 mg Zinc sulfate [C05BA] Vasoprotectives > Antivaricose therapy > Heparins or heparinoids for topical use Trombless gel 1000 IU/1 g Trombless Plus Heparin + Troxerutin+ Dexpanthenol+ Benzocaine Heparin ointment Heparin + Benzocaine + Benzylnicotinat ointment 100 IU+40 mg+800 mcg /1 g [C07AG] Alpha and Beta Blocking Agents Carvedilol Carvedilol tab. 12.5 mg/25 mg [C09AA] Agents acting on the renin-angiotensin system > ACE inhibitors, plain Captopril Captopril tab. 25 mg/50 mg [C10AA] Lipid modifying agents > HMG CoA reductase inhibitors Cardiostatin Lovastatin tab. 20 mg/40 mg D Dermatologicals [D01AC] Antifungals for topical use > Antibiotics Clotrimazole [D01AE] Other antifungals for topical use Fungoterbine Terbinafine Fungoterbine Terbinafine Fungoterbine Neo Terbinafine + Urea gel 10 mg+100 mg/1 g Fungoterbine Neo Terbinafine + Urea cream 10 mg+100 mg/1 g [D01BA] Antifungals for systemic use Fungoterbine Terbinafine tab. 250 mg [D03AX] Preparations for treatment of wounds and ulcers > Cicatrizants Depantol Dexpanthenol + Chlorhexidine cream 525 mg+16 mg/1 g [D06AA] Antibiotics for topical use Tetracycline Tetracycline ointment 3% [D06C] Antibiotics and chemotherapeutics, combinations Levomecol Chloramphenicol + Methyluracil ointment 7.5 mg+40 mg/1 g [D07AA] Corticosteroids, weak (group I) for topical use Hydrocortisone Hydrocortisone ointment 1% Prednisolone Prednisolone ointment 0.5% [D07AC] Corticosteroids, potent (group III) for topical use Sinaflan Fluocinolone acetonide liniment 0.025% Sinaflan Fluocinolone acetonide ointment 0.025% [D08AC] Antiseptics and disinfectants > Biguanides and amidines Chlorhexidine Chlorhexidine solution for topical use 0.05% [G] Genito urinary system and sex hormones [G01AA] Antibiotics Nystatin Nystatin supp. vagin. 250 th.IU N10 [G01AB] Arsenic compounds Acetarsol+ Boric acid + Dextrose supp. vagin. 250 mg+300 mg+ 300 mg Ready [G01AF] Imidazole derivatives Livarole Ketoconazole supp. vagin. 400 mg [G01AX] Other antiinfectives and antiseptics Chlorhexidine supp. vagin. 16 mg Chlorhexidine tab. vagin. 16 mg Hexicon D Chlorhexidine supp. vagin. 8 mg Povidone-iodine supp. vagin. 200 mg [G02BB] Intravaginal contraceptives Benzalkonium chloride supp. vagin. 18.9 mg Benzalkonium chloride gel vagin. 1.2% Benzalkonium chloride tab. vagin. 20 mg [G04BX] Urologicals Depantol Dexpanthenol + Chlorhexidine supp. vagin. 100 mg+16 mg [J] Antiinfectives for systemic use [J01MA] Antibacterials for systemic use > Fluoroquinolones Ofloxacin Ofloxacin tab. coated 200 mg [J02AC] Antimycotics for systemic use > Triazole derivatives Fluconazole Fluconazole caps. 50 mg/150 mg [J04AK] Drugs for treatment of tuberculosis Pyrazinamide Pyrazinamide tab. 500 mg/750 mg Ethambutol Ethambutol tab. 400 mg/800 mg [J05AB] Antivirals for systemic use > Direct acting antivirals > Nucleosides and nucleotides Ribavirin tab. 200 mg Ribavirin caps. 200 mg [M] Musculo-skeletal system [M01AB] Antiinflammatory and antirheumatic products > Acetic acid derivatives and related substances Diclovit Diclofenac supp. rect. 50 mg [M01AC] Antiinflammatory and antirheumatic products > Oxicams Meloxicam tab. 7.5 mg/15 mg [M01AX] Other antiinflammatory and antirheumatic agents, non-steroids Chondroxide Chondroitin sulfate tab. 250 mg [M02AA] Topical products for joint and muscular pain > Antiinflammatory preparations, non-steroids Diclovit Diclofenac [M02AX] Other topical products for joint and muscular pain Chondroxide Chondroitin sulfate gel 50 mg/1 g Chondroxide Chondroitin sulfate + Dimethyl sulfoxide ointment 50 mg+100 mg/1 g [N] Nervous system [N02BB] Analgesics and antipyretics > Pyrazolones Metamizole sodium supp. rect. for children 100 mg/250 mg Ready [N02BE] Analgesics and antipyretics > Anilides Cefecon D Paracetamol supp. rect. for children 50 mg/100 mg/250 mg [N02CC] Antimigraine preparations > Selective serotonin (5HT1) agonists Trimigren Sumatriptan supp. rect. 25 mg/50 mg [N06AX] Antidepressants Azaphen MB Pipofezine tab. mod. release 150 mg [N06BX] Psychostimulants and nootropics Piracetam + Cinnarizine tab. 400 mg+25 mg Vinpocetin Vinpocetine [N07CA] Antivertigo preparations Betahistine tab. 8 mg/16 mg/24 mg
Report on New Patented Drugs - Cialis Under its transparency initiative, the PMPRB publishes the results of the reviews of new patented drugs by Board Staff, for purposes of applying the PMPRB’s Excessive Price Guidelines (Guidelines) for all new active substances introduced after January 1, 2002. Brand Name: Cialis Generic Name: Patentee: Indication - as per product mon
23. What should the doctors treating dengue do?Patients suspected to be suffering from dengue haemorrhagic feveror dengue shock syndrome should be admitted to a hospital withoutdelay. The progress of these patients should be monitored regularlyat 1-2 hours interval. Platelet counts and haematocrits should bemonitored repeatedly to review the progress of patients. If thehaematocrit levels f