EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE LAUSANNE POLITECNICO FEDERALE DI LOSANNA
SWISS FEDERAL INSTITUTE OF TECHNOLOGY LAUSANNE
Prof. Giovanni Dietler
Laboratoire de Physique de la Matière Vivante
Institut de Physique des Systèmes Biologiques
CH-1015 Lausanne, Suisse
Tél (+41) 21 693 04 46
Fax (+41) 21 693 04 22
email: [email protected]
Vous êtes conviés au séminaire qui se tiendra
le mardi 9 avril à 10h00 dans la salle BSP 318
Light-emitting lithium fluoride thin-films for nanoscale radiation
imaging detectors and bio-photonics
Dr. Rosa Maria Montereali
Photonics Micro- and Nano-structures Laboratory,
Point defects in insulating materials are successfully used for radiation detectors. Among them, colour centres in lithium fluoride (LiF) are well known for application in dosimeters and in light-emitting devices and lasers . At ENEA, LiF thin-film imaging detectors for extreme ultraviolet radiation (EUV), soft X-rays  and hard X-rays, based on photoluminescence from aggregate electronic defects in LiF, are currently under development for imaging application with laboratory radiation sources , as well as large-scale facilities . After X-ray exposure, the latent images stored in the LiF thin layers are read with fluorescence optical microscopy techniques.
Among the peculiarities of these LiF solid-state radiation imaging detectors, noteworthy ones are their very high intrinsic spatial resolution (50 - 250 nm) across a large field of view ( > 1 cm2) and versatility. Recently they were proposed also for neutron and proton beams imaging.
Their photoluminescence properties will be discussed together with an overview of results obtained in nano-bio-photonics [2,3,4].
 R.M.Montereali, Point Defects in Thin Insulating Films of Lithium Fluoride for Optical Microsystems,
in Handbook of Thin Film Materials, H.S.Nalwa ed., Vol.3: Ferroelectric and Dielectric Thin Films, 2002, Academic Press, Ch.7, pp.399-431.
 G.Baldacchini, S.Bollanti, F.Bonfigli, F.Flora, P.Di Lazzaro, A.Lai, T.Marolo, R.M.Montereali, D.Murra, A.Faenov, T.Pikuz, E.Nichelatti, G.Tomassetti, A.Reale, L.Reale, A.Ritucci, T.Limongi, L.Palladino, M.Francucci, S.Martellucci and G.Petrocelli, A Novel Soft X-Ray Submicron Imaging Detector Based on Point Defects in LiF,
Review Scientific Instruments 76(2005)113104-1,12 (Also selected for publication in the Virtual Journal of Biological Physics Research 10(11), December 1, 2005).
 D.Hampai, S.B.Dabagov, G.Della Ventura, F.Bellatreccia, M.Magi, F.Bonfigli, and R.M.Montereali, High-resolution X-ray imaging by polycapillary optics and lithium fluoride detectors combination
, Europhysics Letters 96 (2011) 60010,1-4.
 R.M.Montereali, F.Bonfigli, G.Dietler, L.Gregoratti, M.Kiskinova, R.Larciprete, T.Marolo, S.K.Sekatskii, Luminescent Nanostructures Based on Colour Centres Produced in LiF Films by Direct Writing with an X-Ray Microprobe
, physica status solidi (c) 2,1(2005)298-301
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Marta Rendon, MD,a Mark Berneburg, MD,b Ivonne Arellano, MD,c and Mauro Picardo, MDd¨bingen, Germany; Mexico City, Mexico; and Rome, ItalyTreatment of melasma involves the use of a range of topical depigmenting agents and physical therapies. Varying degrees of success have been achieved with these therapies. The Pigmentary Disorders Academy(PDA) undertook to evaluate the clinical efficacy of th