Drug Delivery to the Lungs 21 8th – 10th December 2010 Wednesday 8th December 2010 Coffee & Registration
12.00 – 13.30 Networking Buffet Lunch in Exhibition Hall Welcome and opening remarks: Georgina Fradley, Chair, DDL Committee Session 1: Probing in vivo drug delivery - potential applications to bio- equivalence Chairs: Omar Usmani, Gary Pitcairn, DDL Committee
Development of Idealized Throat Replicas for Inhaler Testing Warren H. Finlay, University of Alberta
The highs and lows of pharmacokinetics in determining the equivalence of inhaled medicinal products
Professor Glyn Taylor, Welsh School of Pharmacy, Cardiff University 15.10 – 15.50 Posters, Exhibition & Coffee
Utilizing In Vivo Lung Imaging Techniques to Assess Pulmonary Drug Delivery
Professor Beth, L. Laube, The Johns Hopkins University School of Medicine, Baltimore, Maryland USA
Regulatory Perspective on Bioequivalence Studies for Inhaled Products
Dr S Dissayanake, Mundipharma Research Ltd Chairmans’ comments
A system for efficient and dose-controlled delivery of liquid substances to in vitro cell models of the lung epithelium
Otmar Schmid, Institute of Lung Biology and Disease, Germany
Application of a Respiratory PBPK Model for Simulating Pulmonary Administration of Fluticasone Propionate in Humans
Dr S Ray Chaudhuri, Simulations Plus, Inc
18.00 – 20.00 Exhibitor Drinks Reception with Entertainment sponsored by Vectura Group plc Thursday 9th December 2010 - AM Registration and Coffee and Poster Viewing
Dr Stephen Newman, Scientific Consultant, UK Session 2: Advances in formulation and analytical science Chair: Craig Davies-Cutting, Ph.D, Director R&D, Catalent Pharma Solutions
Ventilator Aerosol Delivery System (VADS): Concept for Rapid Delivery of Aerosolized Bronchodilators to Adult Patients on Mechanical Ventilation
Dr Jolyon Mitchell, Trudell Medical International, Canada
Electrostatic charge: we can measure it but does it really influence dry powder inhalation formulations
Dr Daniela Traini, Advanced Drug Delivery Group, Faculty of Pharmacy, The University of Sydney, Australia
The use of NMR in pMDI Development Dr Dave Martin, AstraZeneca, UK
10.35 – 11.20 Posters, Exhibition & Coffee
Widening the lens: Re-evaluating the Influence of Size and Morphology of DPI Carrier Particle Performance
Assistant Professor Hugh Smyth, Ph.D., College of Pharmacy, The University of Texas at Austin, USA
Novel Engineered Particle Formulation For Inhaled PYY(3-36) and Demonstration of Appetite Suppression In A Mouse Model
Mr D Vodak, Bend Research Inc, New Mexico, USA What on Earth Singing For BreathingTM - Effects of singing lessons in patients with COPD A Randomised Control Trial Victoria Lord, Specialist Physiotherapist, Royal Brompton & Harefield NHS Foundation Trust, UK Thursday 9th December 2010 – PM 12.30 – 14.00 Lunch plus Exhibition and Posters Session 3: The Pat Burnell New Investigator Award Chairs: Phil Haywood, Ben Forbes, Omar Usmani, Ketan Sharma, DDL Committee
Effect of lactose fines on fluidization properties and in vitro performance of Handihaler Hanne Kinnunen, University of Bath, UK
Optimisation of Dry Powder Inhalers through Robust CFD Simulation of Air Classifiers Sean Cheng, University of Cambridge
Surface modification of mannitol inhaler carrier particles via spray drying Eva Littringer, Research Center Pharmaceutical Engineering GmbH, Austria
Comparison of in vitro methods to determine nasal versus lung deposition of a protein formulation Regina Scherliess, Christian Albrecht University, Germany
Evaluation and modelling of the aerosolisation and break-up of agglomerated systems in dry powder inhalers
William Wong, University of Sydney, Australia
Ultrafast Analysis of Pressurised Metered Dose Inhaler (pMDI) by Direct Spray Mass Spectrometry (Direct Spray-MS)
Hitesh Raghvani, University of London, UK
15.30 – 16.00 Posters, Exhibition & Coffee What on Earth Pioneers of Inhalation II; French kisses and steamy salons! Mark Sanders UK Session 4: Exploring the World of Dry Powder Inhalers Chair: Alex Bell, 3M
Non-destructive examination of inhalation blisters using X-ray computed micro-tomography
K. Lien Nguyen, GlaxoSmithKline, UK
What factors dominate the performance of conventional dry powder inhalation formulations? Associate Professor Paul M Young, Advanced Drug Delivery Group, Faculty of Pharmacy, University of Sydney, Australia
Direct observation of particle dispersion mechanisms in DPI using particle image velocimetry technique Dr. M. Teresa Carvajal, Purdue University, Germany
Engineering of Dry Powder Inhaler Formulation: The Colloidal Science Approach Jag Shur, University of Bath, UK 17.45 – 19.30 Poster Drinks Reception sponsored by The Technology Partnership Friday 10th December 2010
08.15–9.00 Registration and Coffee Chair: Phil Haywood, DDL Committee Karen Pickering, MBE, Asthma UK Ambassador Session 5: Increasing chances of success in early inhaled developments
Introduction of Session 5 Speakers Chair: Georgina Fradley, DDL Committee
How does Airflow Resistance Affect Inspiratory Characteristics as a Child grows into an Adult? Mr D Harris, Sagentia Ltd, UK
Inhaled nanoparticle toxicity assay optimization: dose, size and oxidative potential
Abhinav Kumar, King’s College London, UK What on Earth
Mucociliary Transport & the “Unusually Thick” Paradox Mr R Hall, Mucokinetica Limited, UK
10.50 – 11.50 Posters, Exhibition and Coffee
Beyond FEV1 - Assessing 'small' airways Dr. Omar S Usmani, MBBS MRCP FHEA PhD, Clinical Senior Lecturer & Consultant Physician, National Heart and Lung Institute, Imperial College London & Royal Brompton Hospital
The development of a new rapid screening test for evaluating the non-stick performance of MDI canisters P A Jinks, 3M Drug Delivery Systems, UK
Monitoring Systems for Inhaled Medication
Mr Tony Dyche, Respironics Respiratory Drug Delivery (UK) Ltd, UK
Collaborative efforts to understand the fate of drugs delivered to the lungs Dr Ben Forbes, King’s College London Concluding Remarks and Conference Close Georgina Fradley, Chair, DDL Committee http://www.ddl-conference.org.uk/
CURRICULUM VITAE Kay M. Hood 1600 Nottingham Knoll Drive Jacksonville, FL, 32225 904-256-7626 Florida RN License 3381472, Licensed as an ARNP, 2000-present Georgia RN License R64505, Licensed as an ARNP 1981-present NCC Certified Women’s Health Nurse Practitioner 1982-present NCC Certified Reproductive Endocrinology/Infertility 1989-present EDUCATION University of Flo
Human Ultracell Anti-Ageing Vaccine Introduction The “Institute of Biological Research” of Biocell Ultravital has worked tirelessly on cellular, hormonal and enzymotherapy treatments and devoted many years to a research that have been capturing an enormous interest among the Scientific community. Their rather controversial treatments have been braking through the field because th
Drug Delivery to the Lungs 21