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November 2010 | Volume 68 | Number 3 Closing Opportunity Gaps Pages 32-36 The Myth of Pink and Blue Brains Lise Eliot If educators hope to close gender gaps, they must abandon the notion of a male and female brain.
Gender differences are a hot topic. But much of the recent discussion about
boys' and girls' learning has generated more heat than light. As a
neuroscientist who has studied children's cognitive and emotional abilities
and, in particular, analyzed gender differences in children's brains, I hope to
help set the record straight on this incendiary subject.
Boys and girls differ in many ways—in physical activity level; self-control; and performance levels in reading,
writing, and math. Above all, they differ in interests. But most of these differences are nowhere near as large
as popular ideas about a "Mars-Venus" gulf imply, nor are they as "hardwired" as current discourse portrays.
The truth is that neuroscientists have identified very few reliable differences between boys' and girls' brains.
Boys' brains are about 10 percent larger than those of girls, and boys' brains finish growing a year or two
later during puberty (Lenroot et al., 2007). But these global differences reflect physical maturation more than
Few other clear-cut differences between boys' and girls' neural structures, brain activity, or neurochemistry
have thus far emerged, even for something as obviously different as self-regulation. Boys and girls, on
average, differ in self-regulatory behavior, with girls showing better ability to sit still, pay attention, delay
gratification, and organize a take-home folder, for instance. We know that self-regulatory abilities depend on
the prefrontal cortex of the brain, but neuroscientists have thus far been unable to show that this area
develops earlier or is more active in girls (Barry et al., 2004).
The same is true of gender differences in the adult brain. In spite of what you may have read, women do not
have a larger corpus callosum,1 process language in a more symmetrical fashion, or have higher circulating
levels of serotonin compared with men. The latest high-resolution MRI studies reveal small differences in
brain lateralization or "sidedness" (Liu, Stufflebeam, Sepulcre, Hedden, & Buckner, 2009) and functional
connectivity (Biswal et al., 2010), on the order of three-tenths of a standard deviation, meaning there is more
overlap between average males' and females' brains than differences between the average brain of each
gender. These studies, based on thousands of subjects around the world, give us a better picture of the true
size of neurologic sex differences than do the cherry-picked, single studies of a few dozen men and women
that are often cited as proof of evolutionarily programmed gender differences.
Our actual ability differences are quite small. Although psychologists can measure statistically significant
distinctions between large groups of men and women or boys and girls, there is much more overlap in the
academic and even social-emotional abilities of the genders than there are differences (Hyde, 2005). To put
it another way, the range of performance within each gender is wider than the difference between the
Of course, teachers know this. Teachers recognize that girls or boys can be strong readers. On the
playground, about one-third of girls are physically more active than the average boy. When it comes to
academic achievement and even classroom behavior, gender is a very poor predictor of any individual
So What's Behind Gender Gaps?Society as a whole, however, cannot ignore the striking gender gaps in academic performance. Girls have
out-performed boys in reading and boys have outscored girls in math (although by a smaller margin) on the
National Assessment of Educational Progress (NAEP) in every year assessed since 1971 (U.S. Department
of Education, 2005). Similar gender gaps exist on the Program for International Student Assessment (PISA)
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(Else-Quest, Hyde, & Linn, 2010).
At first glance, this stability suggests there is something inherently different about boys' and girls' academic
abilities. But a closer look reveals that the gaps vary considerably by age, ethnicity, and nationality. For
example, among the countries participating in PISA, the reading gap is more than twice as large in some
countries (Iceland, Norway, and Austria) as in others (Japan, Mexico, and Korea); for math, the gap ranges
from a large male advantage in certain countries (Korea and Greece) to essentially no gap in other
countries—or even reversed in girls' favor (Iceland and Thailand). What's more, a recent analysis of PISA
data found that higher female performance in math correlates with higher levels of gender equity in individual
This suggests that environmental factors are important in shaping gender gaps. The truth is that no mental
ability—or ability difference—is "hardwired" into the brain. Abilities develop in a social-cultural context that
includes each child's opportunities, relationships, sense of identity, and more. Biologists call such
development epigenetic. Environmental factors—ranging from diet and chemical exposure to less tangible
influences like parenting styles—are known to alter DNA structure, gene expression, and an organism's
lifelong brain and behavioral function (Champagne & Curley, 2005). When it comes to gender gaps, boys
and girls start out a little bit different, but these differences become rapidly magnified by a culture that sees
them—and encourages them to see themselves—as fundamentally different creatures.
Three Little Differences—and How They GrowThree small, early biases appear to be programmed by prenatal hormone exposure or sex-specific gene
Baby boys are modestly more physically active than girls (Campbell & Eaton, 1999).
Toddler girls talk one month earlier, on average, than boys (Fenson et al., 1994).
Boys appear more spatially aware (Quinn & Liben, 2008).
Such differences contribute to each gender's well-known toy preferences, which surface in the second year
of life (Servin, Gohlin, & Berlin, 1999). Boys prefer more active playthings, like trucks and balls; girls choose
more verbal-relational toys, especially dolls. In each of these cases, however, boy-girl differences are
magnified through parental treatment. For example, parents encourage more physical risk-taking in sons
than in daughters (Morrongiello & Dawber, 2000); mothers generally talk more to preschool-aged daughters
than sons (Leaper, Anderson, & Sanders, 1998); and parents discourage "gender-inappropriate" play,
especially in terms of boys showing too much interest in sister's Barbie collection (Lytton & Romney, 1991).
This is important, because children develop the skills they will bring into the classroom through such early
play. Simply put, girls spend more time talking, drawing, and role-playing in relational ways, whereas boys
spend more time moving, targeting, building, and role-playing as heroes. Each activity is beneficial, but
because of the potency of early experience on children's brain wiring, the differences between typical "girl"
and "boy" play have deep consequences for cognitive and emotional function.
For example, as boys and girls progress through childhood, clocking very different amounts of time throwing,
catching, constructing, and playing high-speed driving and targeting games, their spatial skills grow
increasingly disparate, with boys scoring higher in this area. The ability to visualize three-dimensional
objects and their orientations, distances, and trajectories is important in higher math, science, and
mechanical work—domains in which boys eventually pull ahead.
Alternatively, consider verbal skills. Thanks to their extra conversation with peers and parents, girls' small
verbal advantage balloons by kindergarten into a significant gap in phonological awareness, the key
stepping stone for learning to read. By 3rd grade, 20 percent more girls than boys score in the proficient
range as readers, according to NAEP data—a gap that grows to 38 percent by 8th grade (Lee, Grigg, &
Donahue, 2007) and a startling 47 percent by the end of high school (Grigg, Donahue, & Dion, 2007).
The numbers are stark, but they reveal that the reason boys don't read and write as well as girls has little to
do with innate brain wiring and everything to do with the reality that girls engage more than boys with words:
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talking, reading, journal writing, or endless text-messaging. Only 25 percent of teenage boys around the
world cite reading as one of their favorite hobbies, compared with 45 percent of teenage girls (Organisation
for Economic Cooperation and Development, 2010).
So if we want to tackle academic gaps between boys and girls, we need to start early, nurturing skills and
attitudes that will better prepare both genders for the modern classroom. We also need to make sure that the
classroom remains a place where students' potential is broadened, rather than narrowed through misguided
beliefs. As always, the best way to do this is to focus on each child's unique combination of cognitive and
Navigating Gender DifferencesIn spite of claims—and intentions—to the contrary, few parents or teachers are truly gender neutral. The
good news is that attempts at gender equity do make a difference. Students develop more stereotyped
attitudes in classrooms that emphasize gender (such as by lining up boys and girls separately) and more
egalitarian attitudes where it's deemphasized (Hilliard & Liben, in press).
So how should teachers pay attention to gender? Very carefully. As with all types of diversity, the challenge
is to respect and honor differences without turning them into self-fulfilling prophecies. Just as we would
never try to guess a student's math skill on the basis of skin or eye color, we must avoid prejudging any
student's verbal, athletic, scientific, artistic, leadership, analytical, or social ability on the basis of
We must challenge gender stereotypes for both sexes. In mainstream U.S. culture, girls are rewarded for
behaving like boys more than the other way around—which is great for girls' math and athletic skills, but not
for boys' verbal and relational abilities. Boys hear that "girls can do anything" whereas the boys get boxed
into smaller corners by their presumed limitations ("Boys are less verbal"); teachers' prohibitions ("No
running"); and peers' narrow views of masculinity ("Art is gay"). Might this be why girls excel in many areas,
while boys' success is shrinking to sports and a few select curricular zones?
Here are a few suggestions for reducing opportunity gaps between boys and girls:
Avoid stereotyping. I suspect most teachers try to do this, but I fear that the recent focus on boy-girl
differences and claims of "hardwiring" have caused things to slip backwards. Some news reports about
single-gender programs describe teachers guiding students into stereotyped activities, for instance, giving
girls quiet spaces to "sit and discuss their feelings" while boys get extra opportunities for competition and
physical play (Tyre, 2005). This approach is wrong: Both sexes need more physical exercise, and both need
to be comfortable blending competition and cooperation. Appreciate the range of intelligences. Beyond the three Rs lie many zones of performance in which
individual students may excel but which aren't typically recognized at school. Howard Gardner brought
nontraditional kinds of intelligence and skill to teachers' attention years ago but with the new back-to-basics
focus, some important domains—such as the arts and kinesthetic ability—have been forgotten. Broadening
the range of abilities that we teach and affirm can help more students feel successful at school. Strengthen spatial awareness. Spatial skills are arguably the most overlooked nontraditional abilities in the
curriculum. Yet spatial cognition is important for understanding such areas as fractions, proportionality,
calculus, geography, physics, and chemistry. Research supports the idea that practice in activities requiring
spatial awareness improves such skills (Newcombe, Mathason, & Terlecki, 2002), but most training in this
domain happens outside school. Beginning in preschool, teachers should formally teach spatial and
mechanical skills using puzzles, map reading, targeting sports, and building projects that get students
Engage boys with the word. Parents and educators alike need to do a better job with this, starting early with
the verbal and literary immersion that builds vocabulary, phonologic skill, and a love of books. The simple
equation, "Language in = Language out" should remind teachers of the importance of engaging boys in
one-on-one dialogue, word play, stories, songs, and every kind of text. Once they begin formal reading
instruction, boys benefit from a wide variety of reading material that appeals to their sense of humor and
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frequent interest in action, adventure, and nonfiction.
Writing ability shows an even larger gender gap, but in a world that produced Shakespeare and Stephen
King, it's absurd to suggest that boys are constitutionally incapable of writing as well as girls. The solution is
time on task. Beginning in preschool, teachers should emphasize "mark-making" to promote writing using
vivid markers, crayons, charcoal, or paint on large surfaces like appliance boxes—or fun ones like portable
slates. The goal is not formal printing, but symbolic expression and fine-motor practice. Although
penmanship is important, divorce it from composition by allowing students to dictate or type their thoughts. Recruit boys into nonathletic extracurricular activities. When did the school newspaper, yearbook, and
student council become all-female clubs? Unfortunately, many of these activities have reached a tipping
point; when the number of boys falls below 25 percent, it becomes—perplexingly—"unmasculine" to join the
chorus or run for class president. Just as we'd be appalled to host a science club without girls, we should not
accept boys' absence from a wider variety of campus activities. Bring more men into the classroom. The number of male teachers in elementary school has declined
precipitously since the 1980s. We need to increase the ranks of young men who enter teaching, and bring
more fathers and adult males into preschool and elementary classrooms as role models for intellectual
Treat teacher bias seriously. There still are teachers who believe "girls are good at reading and boys are
good at math." There still are teachers who cannot tolerate physical exuberance or coloring outside the
lines. Considering the potent effect of teacher expectations on student performance, we must train teachers
about potential bias and evaluate them with respect to it. Just as girls have benefited from efforts to root out
antifemale bias, boys deserve protection from teachers who may—consciously or unconsciously—regard
In the past 15 years, claims about hardwired differences between boys and girls have propagated virally,
with no genuine neuroscientific justification. In reality, culture, attitudes, and practices influence boy-girl
academic gaps far more than prenatal testosterone does. The sooner teachers open their eyes to such
influences, the sooner we can bring out the best in every child.
Barry, R. J., Clarke, A. R., McCarthy, R., Selikowitz, M., Johnstone, S. J., & Rushby,J. A. (2004). Age and gender effects in EEG coherence: I. Developmental trends innormal children. Clinical Neurophysiology, 115, 2252–2258.
Bishop, K. M., & Whalsten, D. (1997). Sex differences in the human corpus callosum:Myth or reality? Neuroscience and Biobehavioral Reviews, 21, 581–601.
Biswal, B. B., Mennes, M., Zuo, X.-N., Gohel, S., Kelly, C., Smith, S. M., et al. (2010). Toward discovery science of human brain function. Proceedings of theNational Academy of Sciences USA, 107, 4734–4739.
Campbell, D. W., Eaton, W. O. (1999). Sex differences in the activity level of infants. Infant and Child Development, 8, 1–17.
Champagne, F. A., & Curley, J. P. (2005). How social experiences influence the brain. Current Opinion in Neurobiology, 15, 704–709.
Else-Quest, N. M., Hyde, J. S., & Linn, M. C. (2010). Cross-national patterns ofgender differences in mathematics: A meta-analysis. Psychological Bulletin, 136,103–127.
Fenson, L., Dale, P. S., Reznick, J. S., Betas, E., Thal, D. J., & Pethick, S. J. (1994). Variability in early communicative development. Monographs of the Society forResearch in Child Development, 59(5).
Grigg, W., Donahue, P., & Dion, G. (2007). The Nation's Report Card: 12th-GradeReading and Mathematics 2005 (NCES 2007-468). Washington, DC: U.S.
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Department of Education, National Center for Education Statistics.
Hilliard, L. J., & Liben, L. S. (in press). Differing levels of gender salience inpreschool classrooms: Effects on children's gender attitudes and intergroup bias. Child Development.
Hyde, J. S. (2005). The gender similarities hypothesis. American Psychologist, 60,581–592.
Leaper, C., Anderson, K. J., & Sanders, P. (1998). Moderators of gender effects onparents' talk to their children: A meta-analysis. Developmental Psychology, 34,3–27.
Lee, J., Grigg, W., & Donahue, P. (2007). The Nation's Report Card: Reading 2007(NCES 2007–496). Washington, DC: National Center for Education Statistics,Institute of Education Sciences, U.S. Department of Education.
Lenroot, R. K., Gogtay, N., Greenstein, D. K., Wells, E. M., Wallace, G. M., Closen, L. S., et al. (2007). Sexual dimorphism of brain developmental trajectories duringchildhood and adolescence. NeuroImage, 36, 1065–1073.
Liu, H., Stufflebeam, S. M., Sepulcre, J., Hedden, T., & Buckner, R. L. (2009). Evidence from intrinsic activity that asymmetry of the human brain is controlled bymultiple factors. Proceedings of the National Academy of Sciences USA, 106,20499–20503.
Lytton, H., & Romney, D. M. (1991). Parents' differential socialization of boys andgirls: A meta-analysis. Psychological Bulletin, 109, 267–296.
Morrongiello, B. A., & Dawber, T. (2000). Mothers' responses to sons and daughtersengaging in injury-risk behaviors on a playground: Implications for sex differences ininjury rates. Journal of Experimental Child Psychology, 76, 89–103.
Newcombe, N. S., Mathason L., & Terlecki, M. (2002). Maximization of spatialcompetence: More important than finding the cause of sex differences. In A. McGillicuddy-DeLisi & R. DeLisi (Eds.), Biology, Society and Behavior: TheDevelopment of Sex Differences in Cognition (pp. 183–206). Westport, CT: Ablex.
Organisation for Economic Cooperation and Development. (2010). PISA: Equallyprepared for life? How 15-year-old boys and girls perform in school. Retrieved fromwww.sourceoecd.org/education/9789264063945
Quinn, P. C., & Liben, L. S. (2008). A sex difference in mental rotation in younginfants. Psychological Science, 19, 1067–1070.
Servin, A., Gohlin, G., & Berlin, L. (1999). Sex differences in 1-, 3-, and 5-year-olds'toy-choice in a structured play-session. Scandinavian Journal of Psychology, 40,43–48.
Tyre, P. (2005, September 19). Boy brains, girl brains: Are separate classrooms thebest way to teach kids? Newsweek.
U.S. Department of Education, National Center for Education Statistics. (2005). TheNation's Report Card long-term trend: Trends in average reading scores by gender. Washington, DC. Author. 1 The corpus cal osum is a white matter tract that provides most of the connections between left and right cerebral hemispheres. Some studies have reported that it's larger in the female brain; others
have found it larger in the male brain, but a meta-analysis of 49 studies found no significant difference
in corpus cal osum size between the genders (Bishop & W halsten, 1997). Lise Eliot is associate professor of neuroscience at the Chicago Medical School of Rosalind Franklin University and
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author of Pink Brain, Blue Brain: How Small Differences Grow Into Troublesome Gaps—And What We Can DoAbout It (Houghton-Mifflin-Harcourt, 2010).
nn Vermeiden Sie Stress und Hektik! Verstopfung ist ein ernst zu nehmendes Problem. Sie kann Stress und Hektik können die Darmtätigkeit nach-aber gut behandelt werden. Lassen Sie sich beim Arzt oder in haltig beeinflussen. Nehmen Sie sich – wann immer Weitere Informationen zum Thema Verstopfung bietet Ihnen die kostenlose Broschüre „Verstopfung – Was tun?”, die Sie nn
Biological Sciences 4087 11/17/10 Total: 100 points There are 5 pages and 12 question on this exam. Question 12 is an essay question. 1.(14pts) Fill in the blanks. A. Metformin (used to treat type 2 diabetes mellitus) inhibits the synthesis of phosphoenolpyruvate carboxykinase and glucose-6-phosphatase. These enzymes are part of the pathway (name the pathway): __________________